DESIGN STUDY FOR THE UCSF PROTON FACILITY

加州大学旧金山分校质子设施的设计研究

• 批准号: 3201351
• 负责人: JOSE ALONSO
• 金额: $ 228.06万
• 依托单位: UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-09-30 至 1994-03-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3201351
• 关键词: biomedical equipment development; biomedical equipment safety; biomedical facility; building /facility design /renovation; clinical biomedical equipment; particle accelerators; proton beam; radiation dosage; radiation therapy; safety equipment

The University of California at San Francisco (UCSF) is planning to build a proton therapy facility as a part of its new Comprehensive Cancer Center. The UCSF Proton Facility will be installed in the lower levels of a new building housing research facilities for the Cancer Center, to be located at UCSF's Mount Zion Hospital and Medical Center site. UCSF and LBL are entering into an agreement to advance this project; LBL will design the accelerator, beam transport and beam delivery systems, will oversee their construction and will be responsible for commissioning and initial operation of the Proton Facility at Mount Zion. As construction of the accelerator systems will probably be finished at least one year prior to the new building's completion, the accelerator will be installed within the experimental area of the Bevalac, and connected to the currently-operating treatment facilities. This will allow for full commissioning of the accelerator, from initial operation to full readiness for clinical use of the proton beam, prior to its transport to its permanent location at Mount Zion. Work to be performed this coming year as part of this Grant application is critical to the success of this project. Very early in the year decisions will be made on the major specifications and architecture of the technical systems. The remainder of the time will be spent in full-scale design and costing activities, leading to the production of a Full Design Report. Detailed designs will emerge from very close interfacing between clinical, medical physics, accelerator physics and engineering personnel; final specifications for each element emerging during the course of the year as a result of design, function and cost optimization studies. The design report will include scope and costing of conventional aspects of the project as well; we will be working with A&E representatives of UCSF to integrate the UCSF Proton Facility into the Comprehensive Cancer Center plans. An analysis of regulatory requirements, and costs for compliance documents will be estimated as well. Finally, a model for operations of the facility will be developed, to identify required ongoing operations costs. The Full Design Report will be a blueprint for the entire UCSF Proton Facility, it will be a document essentially suitable as a bid package.

加州大学弗朗西斯科分校（UCSF）计划在 质子治疗设施作为其新的综合癌症的一部分， 中心 加州大学旧金山分校的质子设施将安装在较低的水平 癌症中心的一座新大楼， 位于加州大学旧金山分校的锡安山医院和医疗中心网站。 UCSF 和LBL正在达成一项协议，以推进这一项目; LBL将 设计加速器，束流传输和束流传输系统，将 监督他们的建设，并将负责调试和 锡安山质子设施的初步运作。 建筑 的加速器系统可能至少要一年才能完成 在新大楼完工之前，加速器将安装在 在Bevalac的实验区域内，并连接到 目前正在运行的治疗设施。 这将使充分 加速器的调试，从初始运行到全面运行 准备好质子束的临床使用，在其运输到 它的永久位置在锡安山。 今年要做的工作 作为资助申请的一部分，一年对于本项目的成功至关重要 项目 今年年初将就主要问题作出决定。 技术系统的规格和架构。 其余部分 的时间将用于全面设计和成本计算活动， 从而产生完整的设计报告。 详细设计将 从临床，医学物理， 加速器物理和工程人员.加速器物理和工程人员.最终规范 在这一年中出现的每一个因素， 设计、功能和成本优化研究。 设计报告将 包括项目常规方面的范围和成本; 我们将与UCSF的A&E代表合作， 质子设施纳入综合癌症中心计划。 分析 法规要求，合规文件的成本将 估计也是。 最后，该设施的运作模式将 以确定所需的持续业务费用。 充分 设计报告将是整个UCSF质子设施的蓝图， 这将是一份基本上适合作为一揽子投标文件的文件。