Molecular Characterization and Genetic Analysis of Nutritional Components of Philippine Indigenous Pigmented Rice Germplasm

菲律宾本土色素稻种质营养成分的分子表征及遗传分析

基本信息

  • 批准号:
    BB/N013603/1
  • 负责人:
  • 金额:
    $ 82.16万
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Research Grant
  • 财政年份:
    2016
  • 资助国家:
    英国
  • 起止时间:
    2016 至 无数据
  • 项目状态:
    已结题

项目摘要

Rice is a staple food for more than half of the world's population, with more than 90% of rice being consumed in Asia. Pigmented rice, such as black and red rice is traditionally used for food for special occasion. The consumption of pigmented rice is rapidly growing along with the increasing interest in health-promoting functional food. Pigmented rice contains high level of phytochemicals such as anthocyanin, flavonoids and vitamin E. Antioxidant activity of these phytochemicals helps to scavenge radical oxygen species (ROS) in human cell, thus decrease the risk of degenerative diseases such as cancer, high cholesterol and cardiovascular disease. Since the price of pigmented rice is more than twice that of white rice and the potential of pigmented rice in international market is large, growing pigmented rice as an alternative to or together with white rice will give higher income for Philippines farmers. Currently, the Genetic Resources Division of the Philippine Rice Research Institute (PhilRice) has more than 800 accessions of pigmented rice collected from various regions of the Philippines. These rice accessions may have nutritional and therapeutic components that can be utilized in the breeding and development of new varieties of pigmented rice, but their potentials has not yet been explored. Through this project the Philippine Rice Research Institute (PhilRice), the National Institute of Agricultural Botany (NIAB) and the International Rice research Institute (IRRI) will collaborate to screen and characterize Philippine indigenous pigmented rice germplasm to discover those pigmented rice accessions that can be utilized as new donors for pigmented rice breeding. PhilRice and NIAB will characterize the variation in agro-morphological traits, grain quality, nutritional composition, seed coat colour, antioxidant activity and phytochemical properties (anthocyanins, flavonoids) in the pigmented rice germplasm. In addition, IRRI will determine the genetic diversity of pigmented rice germplasm through SNP genotyping using Illumina Infinium 6K chip. Based on this phenotype and genotype data we will select a Core collection of pigmented rice accessions. This Core collection will represent different classes of morphological traits, grain quality, nutritional value, antioxidant activity, phytochemical profiles and genetic subgroup. This Core collection will be used for a thorough study of the antioxidant components within pigmented rice using HPLC and Liquid Chromatography/Mass Spectrometry (LC/MS) analysis at NIAB. The genetic basis of the known and potentially novel antioxidant components will be undertaken through a genome-wide association screen (GWAS). Based on the results from the GWAS analysis we will choose several rice accessions that can be utilized as donors. We will identify single nucleotide polymorphisms (SNPs) that are closely associated with the phytochemical having high antioxidant activity and develop trait specific SNP markers for marker-assisted selection. SNP markers have the advantage in that they can be used in high-throughput systems, having fast turnaround times and therefore enable breeders to select desirable plant materials in a shorter time.
大米是世界上一半以上人口的主食,亚洲消费了90%以上的大米。色素米,如黑米和红米,传统上用于特殊场合的食物。随着人们对保健功能性食品的兴趣日益增加,色素大米的消费量沿着迅速增长。色素米含有丰富的花青素、类黄酮和维生素E等植物化学物质。这些植物化学物质的抗氧化活性有助于消除人体细胞中的自由基氧物种(ROS),从而降低癌症,高胆固醇和心血管疾病等退行性疾病的风险。由于色素米的价格是白色米的两倍多,色素米在国际市场上的潜力很大,种植色素米作为白色米的替代品或与之一起种植,将使菲律宾农民获得更高的收入。目前,菲律宾水稻研究所(PhilRice)遗传资源部拥有从菲律宾各地收集的800多份色素水稻。这些水稻种质可能具有营养和治疗成分,可用于色素水稻新品种的选育和开发,但其潜力尚未被开发。通过该项目,菲律宾水稻研究所(PhilRice)、国家农业植物研究所(NIAB)和国际水稻研究所(IRRI)将合作筛选和鉴定菲律宾土著色素水稻种质,以发现可用作色素水稻育种新供体的色素水稻种质。PhilRice和NIAB将描述有色水稻种质的农业形态性状、谷物品质、营养成分、种皮颜色、抗氧化活性和植物化学性质(花青素、类黄酮)的变化。此外,IRRI还将利用Illumina Infinium 6 K芯片,通过SNP基因分型,确定有色稻种质的遗传多样性。基于这些表型和基因型数据,我们将选择一个核心收集色素水稻种质。该核心系列将代表不同类别的形态性状、谷物品质、营养价值、抗氧化活性、植物化学特征和遗传亚组。该核心收集将用于NIAB使用HPLC和液相色谱/质谱(LC/MS)分析对色素大米中的抗氧化剂成分进行彻底研究。已知的和潜在的新的抗氧化剂成分的遗传基础将通过全基因组关联筛选(GWAS)进行。根据GWAS分析的结果,我们将选择几个可以用作供体的水稻种质。我们将确定与具有高抗氧化活性的植物化学物质密切相关的单核苷酸多态性(SNP),并开发用于标记辅助选择的性状特异性SNP标记。SNP标记的优点在于它们可用于高通量系统,具有快速周转时间,因此使育种者能够在更短的时间内选择所需的植物材料。

项目成果

期刊论文数量(10)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Mathematical modeling to predict rice's phenolic and mineral content through multispectral imaging.
  • DOI:
    10.1016/j.focha.2022.100141
  • 发表时间:
    2022-10
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Buenafe, Reuben James;Tiozon, Rhowell Jr;Boyd, Lesley A;Sartagoda, Kristel June;Sreenivasulu, Nese
  • 通讯作者:
    Sreenivasulu, Nese
Additional file 3: of Exploring the genetic diversity within traditional Philippine pigmented Rice
附加文件 3:探索传统菲律宾色素大米的遗传多样性
  • DOI:
    10.6084/m9.figshare.8062481
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Mbanjo E
  • 通讯作者:
    Mbanjo E
Nutritional and genetic variation in a core set of Ethiopian Tef (Eragrostis tef) varieties.
  • DOI:
    10.1186/s12870-022-03595-9
  • 发表时间:
    2022-04-28
  • 期刊:
  • 影响因子:
    5.3
  • 作者:
    Ereful, Nelzo C.;Jones, Huw;Fradgley, Nick;Boyd, Lesley;Cherie, Hirut Assaye;Milner, Matthew J.
  • 通讯作者:
    Milner, Matthew J.
Assessing nutritional and genetic variations within foxtail millet (Setaria italica) landraces collected from indigenous communities across the Philippines.
  • DOI:
    10.1016/j.heliyon.2023.e22964
  • 发表时间:
    2023-12
  • 期刊:
  • 影响因子:
    4
  • 作者:
    Nelzo C. Ereful;Jose Arnel O. Reyes;Don Emanuel M. Cardona;Roneil Christian S. Alonday;Nel Oliver B. Mateo;Huw Jones;Lesley Boyd;Evelyn F. Delfin
  • 通讯作者:
    Evelyn F. Delfin
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Lesley Boyd其他文献

Genome-wide association analysis identifies seven loci conferring resistance to multiple wheat foliar diseases, including brown and yellow rust resistance originating from Aegilops ventricosa
  • DOI:
    10.1007/s00122-025-04907-x
  • 发表时间:
    2025-06-02
  • 期刊:
  • 影响因子:
    4.200
  • 作者:
    Keith A. Gardner;Bethany Love;Pauline Bansept-Basler;Tobias Barber;Simon Berry;Nick Bird;Finn Borum;Lesley Boyd;James K. M. Brown;Ruth Bryant;Paul Fenwick;David Feuerhelm;Nick Gosman;Charlotte Hayes;Tina Henriksson;Peter Jack;Rachel Kirby;Matt Kerton;Jacob Lage;Linda Kærgaard Nielsen;Gemma Rose;Rajiv Sharma;Jörg Schondelmaier;Stephen Smith;Pernilla Vallenback;Duncan Warner;Tally I. C. Wright;Camila M. Zanella;James Cockram;Ian J. Mackay;Donal M. O’Sullivan
  • 通讯作者:
    Donal M. O’Sullivan

Lesley Boyd的其他文献

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{{ truncateString('Lesley Boyd', 18)}}的其他基金

Improving the nutritional value and digestibility of rice to address double burden malnutrition in the Philippines and Thailand
提高大米的营养价值和消化率,解决菲律宾和泰国的双重营养不良负担
  • 批准号:
    BB/T008873/1
  • 财政年份:
    2020
  • 资助金额:
    $ 82.16万
  • 项目类别:
    Research Grant
Canada Partnering Award in support of wheat pre-breeding strategies for disease control
加拿大合作奖支持小麦病害控制预育种策略
  • 批准号:
    BB/T019913/1
  • 财政年份:
    2020
  • 资助金额:
    $ 82.16万
  • 项目类别:
    Research Grant
ITAS application to enable a new collaboration between Drs Lesley Boyd (NIAB) and Brent McCallum (AAFC) in support of the BBSRC project BB/N01622XX/1
ITAS 应用程序使 Lesley Boyd 博士 (NIAB) 和 Brent McCallum (AAFC) 之间能够开展新的合作,以支持 BBSRC 项目 BB/N01622XX/1
  • 批准号:
    BB/R010587/1
  • 财政年份:
    2017
  • 资助金额:
    $ 82.16万
  • 项目类别:
    Research Grant
Bilateral BBSRC-Embrapa: Uncovering the genetic and functional basis of the unique leaf rust resistance in the Brazilian wheat variety Toropi
双边 BBSRC-Embrapa:揭示巴西小麦品种 Toropi 独特叶锈病抗性的遗传和功能基础
  • 批准号:
    BB/N01622X/1
  • 财政年份:
    2016
  • 资助金额:
    $ 82.16万
  • 项目类别:
    Research Grant
Australia: UK wheat pre-breeding for resistance to new disease threats - NextGenWheat
澳大利亚:英国小麦预育种以抵抗新疾病威胁 - NextGenWheat
  • 批准号:
    BB/N022033/1
  • 财政年份:
    2016
  • 资助金额:
    $ 82.16万
  • 项目类别:
    Research Grant
UK partnership to support the uptake of new crop varieties by smallholder farmers, and advancements in agricultural and dissemination technologies
英国合作支持小农采用新作物品种以及农业和传播技术的进步
  • 批准号:
    BB/M017516/1
  • 财政年份:
    2015
  • 资助金额:
    $ 82.16万
  • 项目类别:
    Research Grant
BBSRC Embrapa: Uncovering the genetic basis of the unique durable leaf rust resistance in the Brazilian wheat variety Toropi
BBSRC Embrapa:揭示巴西小麦品种 Toropi 独特的持久叶锈病抗性的遗传基础
  • 批准号:
    BB/N004477/1
  • 财政年份:
    2015
  • 资助金额:
    $ 82.16万
  • 项目类别:
    Research Grant
13 ERA-CAP: Functional characterisation and validation of nonhost components in Triticeae species for durable resistance against fungal diseases
13 ERA-CAP:小麦科物种非寄主成分的功能表征和验证,以持久抵抗真菌病害
  • 批准号:
    BB/M004929/1
  • 财政年份:
    2014
  • 资助金额:
    $ 82.16万
  • 项目类别:
    Research Grant
Establishment of a network that supports plant variety testing, advisory services and farmer training in Eastern and Central Africa
建立支持东部和中部非洲植物品种测试、咨询服务和农民培训的网络
  • 批准号:
    BB/M00516X/1
  • 财政年份:
    2014
  • 资助金额:
    $ 82.16万
  • 项目类别:
    Research Grant
Pre-breeding for durable resistance to rust diseases in hexaploid wheat
六倍体小麦持久抗锈病的预育种
  • 批准号:
    BB/K021435/1
  • 财政年份:
    2013
  • 资助金额:
    $ 82.16万
  • 项目类别:
    Research Grant

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控制父母行为的回路的性别、生理状态和遗传背景依赖性分子特征
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