Validating the commercial potential of genetically modified plant oils in aquaculture via full life-cycle replacement of marine feed ingredients

通过海洋饲料成分的全生命周期替代来验证转基因植物油在水产养殖中的商业潜力

• 批准号: BB/N022157/1
• 负责人: Johnathan Napier
• 金额: $ 59.57万
• 依托单位: Rothamsted Research
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FN022157%2F1
• 关键词: Validating; commercial; potential; genetically; modified

Fish-farming (aquaculture) plays a key role in producing animal protein is produced for human consumption. Aquaculture plays a vital role in feeding the world, and as the number of mouths to feed increases, its role in providing nutritious food continues to grow. Fish farming is more efficient than any terrestrial animal production system, but the Achilles heel of aquaculture is the requirement for omega-3 fish oils in the feeds of marine and salmonid species - this is because fish lack the capacity to make these fatty acids, and if they are not provided in their diet, the resulting product is devoid of these health-beneficial fats. Pressure on the oceanic stocks which are used to produce these fish oils has resulted in increased demand for an alternative source of fish oils for use in aquaculture. Our project is to evaluate, using aquaculture industry parameters, the feasibility of using our GM camelina oil (and meal) as a replacement in the commercial production of farmed salmon.

养鱼业（水产养殖）在生产供人类消费的动物蛋白方面发挥着关键作用。水产养殖在养活世界方面发挥着至关重要的作用，随着需要养活的人口数量的增加，其在提供营养食品方面的作用不断增强。养鱼业比任何陆地动物生产系统都更有效率，但水产养殖的致命弱点是海洋和鲑科鱼饲料中需要 omega-3 鱼油 - 这是因为鱼类缺乏制造这些脂肪酸的能力，如果饮食中不提供这些脂肪酸，所得产品就缺乏这些对健康有益的脂肪。用于生产这些鱼油的海洋种群面临的压力导致对用于水产养殖的鱼油替代来源的需求增加。我们的项目是利用水产养殖业参数来评估使用我们的转基因亚麻荠油（和粉）作为养殖鲑鱼商业化生产的替代品的可行性。

项目成果

Profiling Phospholipids within Atlantic Salmon Salmo salar with Regards to a Novel Terrestrial Omega-3 Oil Source.

• DOI: 10.3390/metabo12090851
• 发表时间: 2022-09-10
• 期刊: Metabolites
• 影响因子: 4.1

Oil from transgenic Camelina sativa as a source of EPA and DHA in feed for European sea bass (Dicentrarchus labrax L.).

• DOI: 10.1016/j.aquaculture.2020.735759
• 发表时间: 2021-01-15
• 期刊: Aquaculture (Amsterdam, Netherlands)
• 作者: Betancor MB;MacEwan A;Sprague M;Gong X;Montero D;Han L;Napier JA;Norambuena F;Izquierdo M;Tocher DR
• 通讯作者: Tocher DR

Towards the development of a sustainable soya bean-based feedstock for aquaculture.

致力于开发可持续的大豆基本原料用于水产养殖。

• DOI: 10.1111/pbi.12608
• 发表时间: 2017-02
• 期刊: Plant biotechnology journal
• 影响因子: 13.8
• 作者: Park H;Weier S;Razvi F;Peña PA;Sims NA;Lowell J;Hungate C;Kissinger K;Key G;Fraser P;Napier JA;Cahoon EB;Clemente TE
• 通讯作者: Clemente TE

An oil containing EPA and DHA from transgenic Camelina sativa to replace marine fish oil in feeds for Atlantic salmon (Salmo salar L.): Effects on intestinal transcriptome, histology, tissue fatty acid profiles and plasma biochemistry.

• DOI: 10.1371/journal.pone.0175415
• 发表时间: 2017
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Betancor MB;Li K;Sprague M;Bardal T;Sayanova O;Usher S;Han L;Måsøval K;Torrissen O;Napier JA;Tocher DR;Olsen RE
• 通讯作者: Olsen RE

Oils Derived from GM Crops as Sustainable Solutions to the Supply of Long-Chain Omega-3 for On-Growing Atlantic Bluefin Tuna (Thunnus thynnus L.)

• DOI: 10.3390/fishes7060366
• 发表时间: 2022-11
• 期刊: Fishes
• 影响因子: 2.3
• 作者: M. B. Betancor;M. Sprague;D. González-Silvera;A. Ortega;F. de la Gándara;Xupeng Gong;J. Napier;D. Tocher;G. Mourente