Enabling UK wheat research with the CyVerse UK cyberinfrastructure
Enabling UK wheat research with the CyVerse UK cyberinfrastructure
批准号:
BB/R000662/1
负责人:
Robert Davey
金额:
$36.11万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2017
资助国家:
英国
项目状态:
已结题
起止时间:
2017 至 --
中文摘要
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英文摘要
Bread wheat represents one of the most complex examples of a plant genome, as well as one of the most commercially important in the UK and internationally with over 750 million tonnes harvested annually, 14 million in the UK alone. This juxtaposition creates a range of challenges for biologists and data analysts - how can the balance between needing large amounts of data to answer complex biological questions about wheat genetics and the requirements for analysing this data and be found? Furthermore, the pressing issues of climate change that we face are all too evident. We need to use modern technology to increase productivity and output for our wheat researchers, drive breeding strategies, and benefit the public's nutritional needs.CyVerse represents such a technology, whereby computational resources, data storage, and analytical tools are made available through web-based graphical interfaces for end users or command line interfaces for power users or system administrators. CyVerse UK is the first implementation of the multi-million dollar CyVerse project outside the US, and both systems are interoperable, i.e. able to share their compute and storage services without the user needing to know where their analyses will be taking place. This federation allows a reduction in shared management cost, and an increase in productivity through shared expertise and software development.The use of "the cloud" is commonplace in today's internet era. Users are moving away from storing data on their own devices, but using services hosted by third party providers such as Google, Microsoft, and Amazon. Furthermore, these vendors also supply complete computing environments over the internet, e.g. Amazon Web Services, and Microsoft Azure. However, these resources are not designed for the kinds of scale that are required for wheat researchers to make the most of publicly available and personal datasets, and the costs of running such environments are unclear at best and prohibitive at worst. Therefore, through the deployment of the proposed CyVerse Atmosphere cloud computing platform in the UK, we would be able to supply virtual server resources to users "elastically", i.e. elastic computing resources can be scaled up and down easily by users themselves. In this way, we can provide flexible computing power when and wherever required, to wheat researchers, labs, and breeders. These virtual wheat data analysis labs can be shared with a wider research group, even internationally, promoting collaboration and knowledge transfer.
期刊论文(8)
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DOI:
10.1101/782771
发表时间:
2019-09
期刊:
bioRxiv
影响因子:
--
作者:
[Anthony Etuk;Felix Shaw;Alejandra N. González-Beltrán;David Johnson;Marie-Angélique Laporte;P. Rocca-Serra;E. Arnaud;M. Devare;P. Kersey;Susanna-Assunta Sansone;Robert P. Davey]
通讯作者:
Anthony Etuk;Felix Shaw;Alejandra N. González-Beltrán;David Johnson;Marie-Angélique Laporte;P. Rocca-Serra;E. Arnaud;M. Devare;P. Kersey;Susanna-Assunta Sansone;Robert P. Davey
DOI:
10.1016/j.patter.2020.100105
发表时间:
2020-10-09
期刊:
Patterns (New York, N.Y.)
影响因子:
--
作者:
[Arnaud E, Laporte MA, Kim S, Aubert C, Leonelli S, Miro B, Cooper L, Jaiswal P, Kruseman G, Shrestha R, Buttigieg PL, Mungall CJ, Pietragalla J, Agbona A, Muliro J, Detras J, Hualla V, Rathore A, Das RR, Dieng I, Bauchet G, Menda N, Pommier C, Shaw F, Lyon D, Mwanzia L, Juarez H, Bonaiuti E, Chiputwa B, Obileye O, Auzoux S, Yeumo ED, Mueller LA, Silverstein K, Lafargue A, Antezana E, Devare M, King B]
通讯作者:
King B
DOI:
10.1038/s41587-021-01058-4
发表时间:
2022-03
期刊:
Nature biotechnology
影响因子:
46.9
作者:
[Gaurav K, Arora S, Silva P, Sánchez-Martín J, Horsnell R, Gao L, Brar GS, Widrig V, John Raupp W, Singh N, Wu S, Kale SM, Chinoy C, Nicholson P, Quiroz-Chávez J, Simmonds J, Hayta S, Smedley MA, Harwood W, Pearce S, Gilbert D, Kangara N, Gardener C, Forner-Martínez M, Liu J, Yu G, Boden SA, Pascucci A, Ghosh S, Hafeez AN, O'Hara T, Waites J, Cheema J, Steuernagel B, Patpour M, Justesen AF, Liu S, Rudd JC, Avni R, Sharon A, Steiner B, Kirana RP, Buerstmayr H, Mehrabi AA, Nasyrova FY, Chayut N, Matny O, Steffenson BJ, Sandhu N, Chhuneja P, Lagudah E, Elkot AF, Tyrrell S, Bian X, Davey RP, Simonsen M, Schauser L, Tiwari VK, Randy Kutcher H, Hucl P, Li A, Liu DC, Mao L, Xu S, Brown-Guedira G, Faris J, Dvorak J, Luo MC, Krasileva K, Lux T, Artmeier S, Mayer KFX, Uauy C, Mascher M, Bentley AR, Keller B, Poland J, Wulff BBH]
通讯作者:
Wulff BBH
AutoCloner: automatic homologue-specific primer design for full-gene cloning in polyploids.
AutoCloner:自动同源特异性引物设计,用于多倍体中的全基因克隆。
DOI:
10.1186/s12859-020-03601-7
发表时间:
2020
期刊:
BMC bioinformatics
影响因子:
3
作者:
[Coulton A]
通讯作者:
Coulton A
Colombia's cyberinfrastructure for biodiversity: Building data infrastructure in emerging countries to foster socioeconomic growth
哥伦比亚的生物多样性网络基础设施:在新兴国家建设数据基础设施以促进社会经济增长
DOI:
10.1002/ppp3.10086
发表时间:
2019
期刊:
PLANTS, PEOPLE, PLANET
影响因子:
--
作者:
[De Vega J]
通讯作者:
De Vega J
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