ATMOSPHERIC REACTIONS OF SINGLET OXYGEN

单线态氧的大气反应

• 批准号: 3250472
• 负责人: WALTER C EISENBERG
• 金额: $ 5.15万
• 依托单位: ILLINOIS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-07-01 至 1988-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3250472
• 关键词: benzanthracenes; chemical carcinogen; chemical carcinogenesis; chrysenes; environmental contamination; fluorescence microscopy; high performance liquid chromatography; oxidizing agents; respiratory oxygen; spectrometry

Singlet molecular oxygen in the form of the delta state (delta 02) has been identified as a potential atmospheric oxidant. Although ambient levels of delta 02 are not well established, we have been able to generate delta 02 at one atmosphere pressure and study its chemistry. The mean lifetime Tau was determined to be of the order of 0.1 sec and thus, it is long lived enough to react with atmospheric pollutants. We propose that delta 02 is an agent giving rises to low levels of toxic material in the atmosphere. In the hypothesis PAH adsorbed on particulate material absorb sunlight and sensitize the formation of delta 02 from proximate ground state oxygen. Delta 02 then reacts with proximate PAH on particulate surfaces forming oxygenated PAH, many of which are known to be mutagenic and/or carcinogenic. We will investigate the reaction of two PAHs, chrysene and benza[a]anthracene, adsorbed on model particulate with delta 02, and determine if PAH are self-activated (with respect to their mutagenicity) through product studies and Ames testing. The effect of light and then light and oxygen on the reaction of PAH on particle surfaces will also be studied. Product identification and Ames testing will be performed. A detailed analysis of the results will indicate the extent to which delta 02 is involved in the total chemical transformations of photooxidation reactions and whether other processes (Type I or electron transfer processes) are involved.

δ态（δ 02）形式的单线态分子氧已经被发现。 被认为是潜在的大气氧化剂。 虽然环境水平的 德尔塔02还没有很好地建立，我们已经能够生成德尔塔02 研究它的化学性质 平均寿命τ 被确定为0.1秒的量级，因此，其寿命长 足以与大气污染物发生反应。 我们建议德尔塔02是 一种能在大气中产生低浓度有毒物质的物质。 在假设中，吸附在颗粒材料上的PAH吸收阳光， 敏化从接近基态的氧形成δ O2。 然后，Delta O2与颗粒表面上的近端PAH反应， 含氧PAH，其中许多已知具有致突变性和/或 致癌的 我们将研究两种多环芳烃的反应， 苯并[a]蒽，吸附在具有Δ 02的模型颗粒上，以及 确定PAH是否自激活（就其致突变性而言） 通过产品研究和艾姆斯测试。 光的影响，然后 光和氧气对颗粒表面PAH反应的影响也将 研究了 将进行产品识别和艾姆斯试验。 一 对结果的详细分析将表明德尔塔02 参与光氧化的总化学转化 反应和其他过程（I型或电子转移） 过程）。