Metal-organic frameworks at the biointerface

生物界面的金属有机框架

• 批准号: DP170103531
• 负责人: Prof Christian Doonan
• 金额: $ 28.76万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP170103531
• 关键词: Metal; organic; frameworks; biointerface

This project aims to understand the chemistry that governs the crystallisation of metal-organic frameworks (MOF) around functional biomacromolecules and explore these bio-composites’ uses. Functional biomacromolecules, such as proteins, could be applied to biotechnology and Industrial biocatalysis. The project will develop MOF-encapsulated biocatalytic platform materials that allow inherently fragile biomacromolecules to remain active in conditions needed for industrial processes. This project could advance the widespread commercial application of biocatalysts and biosensors.

该项目旨在了解控制功能性生物大分子周围金属有机框架（MOF）结晶的化学，并探索这些生物复合材料的用途。蛋白质等功能性生物大分子可应用于生物技术和工业生物催化。该项目将开发MOF封装的生物催化平台材料，使固有的脆弱生物大分子在工业过程所需的条件下保持活性。该项目将促进生物催化剂和生物传感器的广泛商业应用。