Understanding hyaluronan crosslinking mechanisms in ovulation and inflammation: CryoEM structural and interaction analysis of HC-HA/PTX3 complexes

了解排卵和炎症中的透明质酸交联机制：HC-HA/PTX3 复合物的 CryoEM 结构和相互作用分析

• 批准号: BB/T001631/1
• 负责人: Ralf Richter
• 金额: $ 42.01万
• 依托单位: University of Leeds
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FT001631%2F1
• 关键词: Understanding; hyaluronan; crosslinking; mechanisms; ovulation

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Glycosaminoglycans: What Remains To Be Deciphered?

• DOI: 10.1021/jacsau.2c00569
• 发表时间: 2023-03-27
• 期刊: JACS AU
• 影响因子: 8
• 作者: Perez, Serge;Makshakova, Olga;Angulo, Jesus;Bedini, Emiliano;Bisio, Antonella;de Paz, Jose Luis;Fadda, Elisa;Guerrini, Marco;Hricovini, Michal;Hricovini, Milos;Lisacek, Frederique;Nieto, Pedro M;Pagel, Kevin;Paiardi, Giulia;Richter, Ralf;Samsonov, Sergey A;Vives, Romain R;Nikitovic, Dragana;Ricard Blum, Sylvie
• 通讯作者: Ricard Blum, Sylvie

A quartz crystal microbalance method to quantify the size of hyaluronan and other glycosaminoglycans on surfaces.

• DOI: 10.1038/s41598-022-14948-7
• 发表时间: 2022-06-29
• 期刊: SCIENTIFIC REPORTS
• 影响因子: 4.6
• 作者: Srimasorn, Sumitra;Souter, Luke;Green, Dixy E.;Djerbal, Lynda;Goodenough, Ashleigh;Duncan, James A.;Roberts, Abigail R. E.;Zhang, Xiaoli;Debarre, Delphine;DeAngelis, Paul L.;Kwok, Jessica C. F.;Richter, Ralf P.
• 通讯作者: Richter, Ralf P.

Controlling Superselectivity of Multivalent Interactions with Cofactors and Competitors.

• DOI: 10.1021/jacs.2c06942
• 发表时间: 2022-09-28
• 期刊: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
• 影响因子: 15
• 作者: Curk, Tine;Dubacheva, Galina V.;Brisson, Alain R.;Richter, Ralf P.
• 通讯作者: Richter, Ralf P.