课题基金 / 基金详情

SUBUNIT/DOMAIN INTERACTIONS IN MULTIFUNCTIONAL ENZYMES

SUBUNIT/DOMAIN INTERACTIONS IN MULTIFUNCTIONAL ENZYMES
多功能酶中的亚基/结构域相互作用
批准号:
3275108
负责人:
JOHN A DE MOSS
金额:
$1.77万
依托单位国家:
美国
项目类别:
财政年份:
1980
资助国家:
美国
项目状态:
已结题
起止时间:
1980-05-01 至 1986-12-31

项目摘要

项目成果

JOHN A DE MOSS的其他基金

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相关文献

中文摘要
翻译
反应序列的催化及其整合与调控
英文摘要
The catalysis of reaction sequences and their integration and regulation in the metabolic pathways of the cell depends on organization at several different levels. These include the organization of protein components in the various organelles and compartments at the cell level, the association of specific protein subunits into enzymes or multienzyme complexes and the organization and association of specific protein domains within the structure of the polypeptide subunits. The long range goal of this project is to define the role of subunit and domain interactions in the structure and function of multifunctional enzyme complexes. By utilizing a specific multi-functional enzyme complex from the tryptophan pathway or Neurospora crassa which is amenable to chemical, physical and genetic analysis, we propose to probe domain structure and organization in this multifunctional protein and the role of the interaction of domains and subunits in the expression of enzyme activities.
期刊论文(7)
专著(0)
科研奖励(0)
会议论文
Deletion analysis of domain independence in the TRP1 gene product of Neurospora crassa.
粗糙脉孢菌 TRP1 基因产物中结构域独立性的缺失分析。
DOI: 10.1007/bf00315796
发表时间: 1990
期刊: Molecular & general genetics : MGG
影响因子: --
作者: [Walker,MS, DeMoss,JA]
通讯作者: DeMoss,JA
DOI: --
发表时间: 1988
期刊: The Journal of biological chemistry
影响因子: --
作者: [Pratt,ML, DeMoss,JA]
通讯作者: DeMoss,JA
Anthranilate synthase of Neurospora crassa: reaction and labeling with glutamine analogs.
粗糙脉孢菌的邻氨基苯甲酸合酶:用谷氨酰胺类似物进行反应和标记。
DOI: 10.1016/0003-9861(82)90366-6
发表时间: 1982
期刊: Archives of biochemistry and biophysics
影响因子: 3.9
作者: [Paukert,JL, Henkin,J, KeeseyJr,J, DeMoss,JA]
通讯作者: DeMoss,JA
Orientation of enzymic domains in tryptophan synthase of Neurospora crassa: an immunoblot analysis of TRP3 mutant products.
粗糙脉孢菌色氨酸合酶中酶结构域的方向:TRP3 突变产物的免疫印迹分析。
DOI: 10.1007/bf00328130
发表时间: 1987
期刊: Molecular & general genetics : MGG
影响因子: --
作者: [Matchett,WH, Lacy,AM, DeMoss,JA]
通讯作者: DeMoss,JA
共 7 条
    SUBUNIT/DOMAIN INTERACTIONS IN MULTIFUNCTIONAL ENZYMES
    MOLECULAR BASIS OF CELL FUNCTION
    ASSEMBLY OF A MEMBRANE-BOUND MULTI-ENZYME COMPLEX
    ASSEMBLY OF A MEMBRANE-BOUND MULTI-ENZYME COMPLEX
    海外基金