21ENGBIO: Bioinspired manufacturing of non-Euclidean morphologies

21ENGBIO：非欧几里得形态的仿生制造

基本信息

批准号：
BB/W012715/1
负责人：
Rainer Maria Groh
金额：
$ 12.83万
依托单位：
University of Bristol
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2022
资助国家：
英国
起止时间：
2022 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=BB%2FW012715%2F1
关键词：
21ENGBIO Bioinspired manufacturing non Euclidean

项目摘要

All biological materials we see around us are produced using the natural processes of developmental growth and remodelling. These processes differ markedly from engineering approaches to manufacturing, both at the larger scale of mechanical engineering (e.g. aircraft, cars, and ships) and the smaller scale of synthetic biology (e.g. the production of bioinspired nanomaterials or synthetic proteins) because Nature uses a combination of different materials or different growth rates to create fascinating shapes. For example, the wrinkles at the edges of leaves or the familiar trumpet-like shape of a daffodil are the result of differential growth across space and time. Biological and mechanical engineers can replicate the mechanics of growth using similar physical triggers, such as varying temperatures or the swelling of chemical agents, to manufacture complex and organic shapes that are very costly to manufacture using established industrial manufacturing processes. By controlling and tailoring the expansion and contraction of different materials during manufacturing, this research will open up new manufacturing capabilities at the very large scales of mechanical engineering and the very small scales of synthetic biology. Ultimately, this will lead to new opportunities for creating more efficient bioinspired structures for mechanical engineering applications and novel applications in tissue engineering.

我们周围看到的所有生物材料都是使用发育生长和重塑的自然过程生产的。这些过程与工程方法与制造业明显不同，无论是在机械工程的较大规模上（例如飞机，汽车和船只）和较小的合成生物学规模（例如，生物启发的纳米材料或合成蛋白的产生），因为大自然使用了不同材料或不同生长速率的组合或不同的生长速率，从而创造出了迷人的光泽。例如，叶子边缘的皱纹或水仙花的类似小号的形状是跨时空增长的结果。生物学和机械工程师可以使用类似的物理触发器（例如变化的温度或化学剂的肿胀）复制生长力学，以制造复合和有机形状，这些复合和有机形状是使用既定工业制造工艺制造非常昂贵的。通过控制和调整制造过程中不同材料的扩展和收缩，这项研究将在机械工程非常大的规模和合成生物学的很小规模上开放新的制造能力。最终，这将为机械工程应用和组织工程中的新应用创建更有效的生物启发结构提供新的机会。