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21ENGBIO: Bioinspired manufacturing of non-Euclidean morphologies

21ENGBIO：非欧几里得形态的仿生制造

基本信息

批准号：
BB/W012715/1
负责人：
Rainer Maria Groh
金额：
$ 12.83万
依托单位：
University of Bristol
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2022
资助国家：
英国
起止时间：
2022 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=BB%2FW012715%2F1
关键词：
21ENGBIO Bioinspired manufacturing non Euclidean

项目摘要

All biological materials we see around us are produced using the natural processes of developmental growth and remodelling. These processes differ markedly from engineering approaches to manufacturing, both at the larger scale of mechanical engineering (e.g. aircraft, cars, and ships) and the smaller scale of synthetic biology (e.g. the production of bioinspired nanomaterials or synthetic proteins) because Nature uses a combination of different materials or different growth rates to create fascinating shapes. For example, the wrinkles at the edges of leaves or the familiar trumpet-like shape of a daffodil are the result of differential growth across space and time. Biological and mechanical engineers can replicate the mechanics of growth using similar physical triggers, such as varying temperatures or the swelling of chemical agents, to manufacture complex and organic shapes that are very costly to manufacture using established industrial manufacturing processes. By controlling and tailoring the expansion and contraction of different materials during manufacturing, this research will open up new manufacturing capabilities at the very large scales of mechanical engineering and the very small scales of synthetic biology. Ultimately, this will lead to new opportunities for creating more efficient bioinspired structures for mechanical engineering applications and novel applications in tissue engineering.

我们周围的所有生物材料都是通过发育生长和重塑的自然过程产生的。这些过程明显不同于工程方法的制造，无论是在较大规模的机械工程（如飞机、汽车和船舶）还是较小规模的合成生物学（如生产生物启发的纳米材料或合成蛋白质），因为大自然使用不同材料或不同生长速度的组合来创造迷人的形状。例如，叶子边缘的皱纹或水仙花熟悉的喇叭状形状是跨越空间和时间的差异生长的结果。生物和机械工程师可以使用类似的物理触发因素（如温度变化或化学试剂的膨胀）来复制生长的机制，以制造复杂的有机形状，而使用现有的工业制造工艺制造这些形状非常昂贵。通过在制造过程中控制和调整不同材料的膨胀和收缩，这项研究将在机械工程的大尺度和合成生物学的小尺度上开辟新的制造能力。最终，这将为机械工程应用和组织工程中的新应用创造更有效的生物启发结构带来新的机会。