RAMAN STUDIES OF PORPHYRINS AND RELATED MACROCYCLES

卟啉和相关大环的拉曼研究

基本信息

  • 批准号:
    3289811
  • 负责人:
  • 金额:
    $ 8.16万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    1985
  • 资助国家:
    美国
  • 起止时间:
    1985-07-01 至 1994-11-30
  • 项目状态:
    已结题

项目摘要

The general objectives of the proposed research are to characterize the structural, electronic and magnetic properties of porphyrins, hydroporphyrins and structurally related bio-macrocycles. A variety of methodologies will be used including Resonance Raman (RR), infrared (IR), absorption and electron paramagnetic resonance (EPR) spectroscopies, normal coordinate analysis, and semiempirical quantum force field calculations. The procedures, aims and rationales for the studies are as follows: (1) The RR and IR spectra of a variety of prototypical chlorins, bacteriochlorins and isobacteriochlorins will be characterized in detail. The vibrational data will be analyzed via both conventional normal coordinate and semiempirical quantum force field methods. The semiempirical calculations will be refined and extended to protein prosthetic groups, such as siroheme, heme d1 and cofactor F430, which are not amenable to conventional vibrational analysis procedures because large numbers of isotopomers are not available. The aim of these studies is to provide a foundation for the interpretation of the vibrational data of reduced-pyrrole macrocycles in general. These bench marks are needed (but not generally available) in order to extract structural information from the vibrational spectra of hydroporphyrins in proteins. (2) The RR and IR spectra of pi-cation and pi-anion radicals of various porphyrins and hydroporphyrins will be characterized. Normal coordinate calculations will be performed on these species by using both conventional and semiempirical quantum force field methods. Vibrational and EPR spectra of various metal-reduced hydroporphyrins, such as complexes of Fe(I) and Ni(I), will also be examined. The aim of these studies is to characterize the structural and electronic perturbations induced by the addition or removal of electrons. A quantitative assessment of the effects of oxidation/reduction is needed (but again not generally available) in order to extract structural information from the spectra of oxidized/reduced tetrapyrrolic intermediates in proteins. (3) The RR, IR, EPR and optical spectra of a series of neutral, oxidized and reduced porphyrin and hydroporphyrin dimers and trimers [structure Ln(ring)2, (ring)Ln(ring') and Ln2(ring)3] will be examined. The aim of these studies is to determine the influence of strong pipi interactions on the electronic properties of the complexes and provide a foundation for assessing how such electronic communication might mediate energy and/or electron transfer between tetrapyrrolic prosthethic groups in proteins.
拟议研究的总体目标是描述

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

DAVID F. BOCIAN其他文献

DAVID F. BOCIAN的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('DAVID F. BOCIAN', 18)}}的其他基金

VIBRATIONAL STUDIES OF ENERGY TRANSDUCING PROTEINS
能量转换蛋白的振动研究
  • 批准号:
    3296956
  • 财政年份:
    1988
  • 资助金额:
    $ 8.16万
  • 项目类别:
VIBRATIONAL STUDIES OF ENERGY TRANSDUCING PROTEINS
能量转换蛋白的振动研究
  • 批准号:
    2180030
  • 财政年份:
    1988
  • 资助金额:
    $ 8.16万
  • 项目类别:
VIBRATIONAL STUDIES OF ENERGY TRANSDUCING PROTEINS
能量转换蛋白的振动研究
  • 批准号:
    6525600
  • 财政年份:
    1988
  • 资助金额:
    $ 8.16万
  • 项目类别:
VIBRATIONAL STUDIES OF ENERGY TRANSDUCING PROTEINS
能量转换蛋白的振动研究
  • 批准号:
    2180029
  • 财政年份:
    1988
  • 资助金额:
    $ 8.16万
  • 项目类别:
VIBRATIONAL STUDIES OF ENERGY TRANSDUCING PROTEINS
能量转换蛋白的振动研究
  • 批准号:
    6612528
  • 财政年份:
    1988
  • 资助金额:
    $ 8.16万
  • 项目类别:
VIBRATIONAL STUDIES OF ENERGY TRANSDUCING PROTEINS
能量转换蛋白的振动研究
  • 批准号:
    6192238
  • 财政年份:
    1988
  • 资助金额:
    $ 8.16万
  • 项目类别:
VIBRATIONAL STUDIES OF ENERGY TRANSDUCING PROTEINS
能量转换蛋白的振动研究
  • 批准号:
    2180028
  • 财政年份:
    1988
  • 资助金额:
    $ 8.16万
  • 项目类别:
VIBRATIONAL STUDIES OF ENERGY TRANSDUCING PROTEINS
能量转换蛋白的振动研究
  • 批准号:
    3296958
  • 财政年份:
    1988
  • 资助金额:
    $ 8.16万
  • 项目类别:
VIBRATIONAL STUDIES OF ENERGY TRANSDUCING PROTEINS
能量转换蛋白的振动研究
  • 批准号:
    3296957
  • 财政年份:
    1988
  • 资助金额:
    $ 8.16万
  • 项目类别:
VIBRATIONAL STUDIES OF ENERGY TRANSDUCING PROTEINS
能量转换蛋白的振动研究
  • 批准号:
    3296955
  • 财政年份:
    1988
  • 资助金额:
    $ 8.16万
  • 项目类别:

相似海外基金

MRI: Acquisition of an X-ray Diffractometer for Research and Training in Chemical Structure-Function Studies
MRI:购买 X 射线衍射仪用于化学结构-功能研究的研究和培训
  • 批准号:
    1726630
  • 财政年份:
    2017
  • 资助金额:
    $ 8.16万
  • 项目类别:
    Standard Grant
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了