International Collaboration in Chemistry: Experimental and Theoretical Study of Redox-Active Fe4O4-Cubanes

国际化学合作：氧化还原活性 Fe4O4-古巴烷的实验和理论研究

• 批准号: EP/G002789/2
• 负责人: John McGrady
• 金额: --
• 依托单位: University of Oxford
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2009
• 资助国家: 英国
• 起止时间: 2009 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FG002789%2F2
• 关键词: International; Collaboration; Chemistry; Experimental; Theoretical

This project is based on a collaboration between two groups, one experimental and one theoretical, who share a common interest in the interaction between metal ions in high nuclearity clusters. The proposal has been inspired by our recent characterization of an octanuclear iron cluster, [FeIII8(mu4-O)4(mu-4-R-pz)12X4], (pz = the pyrazolato anion) which contains an Fe4O4 cubane core surrounded by four peripheral FeIII centers. Our fascination with this particular family of clusters stems from their remarkable electrochemical properties: four reversible reduction waves can be accessed in a potential window much narrower than anything seen for the more extensively-studied iron/sulfur analogues. The ability of iron clusters to accommodate large fluctuations in electron count is fundamental to their role in biological electron transfer, and these clusters offer a unique window on the intimate electronic processes involved. We have illustrated the synergy between experiment and theory in these systems in a recent joint publication, where we analyzed the structure and properties of the all-ferric parent compounds. Very recently, we have also succeeded in isolating the 1-electron reduced species, [FeIII8(mu4-O)4(mu-4-R-pz)12X4]-. In this proposal, we seek support to extend our studies to the 1-, 2-, 3- and 4-electron reduced analogues, all of which feature ferric and ferrous centers. The ultimate goal is to characterize as fully as possible each of the mixed-valent states spanning the FeIII8 and FeIII4FeII4 limits observed in the electrochemical experiment. The focus at the University of Puerto Rico will be on the synthesis of new clusters capable of supporting the more highly reduced oxidation levels and their characterization using a wide range of physicochemical techniques. Voltammetry, diffraction, in situ UV-Vis-NIR spectroelectrochemistry and XPS will be conducted 'in-house', while magnetochemical properties, EPR and Mssbauer spectra will be measured in the laboratories of established collaborators who are leaders in their fields. The research team at the University of Glasgow will explore the electronic structure of these compounds using broken-symmetry density functional theory. The aim is to maximize the information content of the physicochemical measurements by establishing a direct correspondence between observation and the underlying electronic structure. Intellectual merit: The study of mixed-valent metal species has long held the attention of chemists, and the interactions between the metal centers have profound implications in both materials and biological chemistry. The Fe8 clusters described in this proposal offer a unique opportunity to study mixed valence in a discrete molecular species across an unprecedented range of oxidation states. Much of the previous work in this area has been limited to di- or tetranuclear clusters, and the presence of eight paramagnetic centers presents a significant increase in complexity.This project will link established research programmes at the University of Puerto Rico and the University of Glasgow, both of which focus on the structure of paramagnetic metal clusters. The approaches of the two groups are quite distinct, one using synthesis and physicochemical measurements, the other theory, and the synergy between the two promises to reveal new insights. The opportunity for young researchers to exchange complementary ideas and expertise through extended stays in international laboratories is a key element of the research programme, and will undoubtedly establish long-lasting links between the two groups. The applicants have a track record of informal collaboration dating back to the early 1990s, and have already published joint papers on a number of topics related to the electronic structure and properties of metal clusters. In all cases, the collaboration has been founded on the synergy between spectroscopy and theory that lies at the heart of this proposal.

这个项目是基于两个小组之间的合作，一个实验和一个理论，谁在高核团簇中的金属离子之间的相互作用有着共同的兴趣。该建议的灵感来自于我们最近对八核铁簇[FeIII 8（mu 4-O）4（mu-4-R-pz）12 X4]（pz =吡唑阴离子）的表征，该簇包含由四个外围FeIII中心包围的Fe 4 O 4立方烷核心。我们对这个特殊的簇家族的迷恋源于它们非凡的电化学性质：四个可逆的还原波可以在一个比更广泛研究的铁/硫类似物更窄的电势窗口中访问。铁团簇适应电子计数大幅波动的能力是它们在生物电子转移中发挥作用的基础，这些团簇为所涉及的密切电子过程提供了一个独特的窗口。在最近的一份联合出版物中，我们已经说明了这些系统中实验和理论之间的协同作用，在那里我们分析了全铁母体化合物的结构和性质。最近，我们还成功地分离了1-电子还原物种[FeIII 8（mu 4-O）4（mu-4-R-pz）12 X4]-。在这个建议中，我们寻求支持，以扩大我们的研究，1-，2-，3-和4-电子还原类似物，所有这些功能铁和亚铁中心。最终的目标是尽可能充分地表征每个混合价态跨越FeIII 8和FeIII 4FeII 4的电化学实验中观察到的限制。在波多黎各大学的重点将是新的集群的合成能够支持更高度降低氧化水平和他们的表征使用广泛的物理化学技术。伏安法、衍射、原位紫外-可见-近红外光谱电化学和XPS将在“内部”进行，而磁化学性质、EPR和穆斯堡尔谱将在各自领域的领导者的实验室进行测量。格拉斯哥大学的研究小组将利用对称性破缺密度泛函理论探索这些化合物的电子结构。其目的是通过建立观测和基础电子结构之间的直接对应关系，最大限度地提高物理化学测量的信息含量。智力优点：混合价金属物种的研究长期以来一直受到化学家的关注，金属中心之间的相互作用在材料和生物化学中具有深远的意义。本提案中描述的Fe 8簇提供了一个独特的机会，可以在前所未有的氧化态范围内研究离散分子物种的混合价。以前在这一领域的许多工作都局限于双核或四核簇，而八个顺磁中心的存在显着增加了复杂性，这个项目将连接在波多黎各大学和格拉斯哥大学的既定研究计划，这两个大学都专注于顺磁金属簇的结构。这两个小组的方法是相当不同的，一个使用合成和物理化学测量，另一个理论，两者之间的协同作用有望揭示新的见解。青年研究人员有机会通过在国际实验室的长期停留交流互补的想法和专门知识，这是研究方案的一个关键因素，无疑将在两个小组之间建立长期的联系。申请人的非正式合作记录可以追溯到20世纪90年代初，并已发表了关于金属簇的电子结构和性质的一些主题的联合论文。在所有情况下，合作都建立在光谱学和理论之间的协同作用上，这是这项提议的核心。

项目成果

Electronic structure and magnetic properties of a trigonal prismatic Cu(II)6 cluster.

• DOI: 10.1039/b907805c
• 发表时间: 2009-07
• 期刊: Dalton transactions
• 影响因子: 4
• 作者: E. Zueva;M. Petrova;R. Herchel;Z. Trávníček;R. Raptis;Logesh Mathivathanan;J. McGrady

Double exchange in a mixed-valent octanuclear iron cluster, [Fe8(µ4-O)4(µ-4-Cl-pz)12Cl4](-).

混合价八核铁簇中的双交换，[Fe8(µ4-O)4(µ-4-Cl-pz)12Cl4](-)。

• DOI: 10.1039/c4dt00020j
• 发表时间: 2014
• 期刊: 2003)
• 作者: Zueva EM

Experimental and theoretical Mössbauer study of an extended family of [Fe8(µ4-O)4(µ-4-R-px)12X4] clusters.

[Fe8(µ4-O)4(µ-4-R-px)12X4] 团簇大家族的实验和理论穆斯堡尔研究。

• DOI: 10.1021/ic101691q
• 发表时间: 2011
• 期刊: Inorganic chemistry
• 影响因子: 4.6
• 作者: Zueva EM