NEUROENDOCRINE REGULATION OF EPISODIC LH RELEASE

本研究计划的总体目标是阐明 脑和内分泌刺激在调节脉冲LH释放。 具体 调查的领域将包括各种中枢神经系统领域对 脉冲式LH释放，神经递质的作用，如血清素或 多巴胺介导的任何观察到的影响，参数脉动LH 释放受影响，即，LH脉冲间期或LH脉冲幅度，以及 雌激素可能改变脑内肾上腺素能功能。

The overall objective of this research program is to clarify the role of the brain and endocrine stimuli in the regulation of pulsatile LH release. Specific areas of investigation will include the influence of various CNS areas on pulsatile LH release, the role of neurotransmitters such as serotonin or dopamine in mediating any observed effects, the parameters of pulsatile LH release affected, i.e., LH interpulse interval or LH pulse magnitude, and possible modification of brain serotoninergic function by estrogen.