PROSPEcT: Ecotoxicology test protocols for representative nanomaterials in support of the OECD sponsorship programme

前景：支持经合组织赞助计划的代表性纳米材料的生态毒理学测试方案

基本信息

批准号：
EP/G043140/1
负责人：
Tamara Susan Galloway
金额：
$ 60.81万
依托单位：
UNIVERSITY OF EXETER
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2009
资助国家：
英国
起止时间：
2009 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=EP%2FG043140%2F1
关键词：
PROSPEcT Ecotoxicology test protocols representative

项目摘要

The proposed research forms an integral part of the PROSPEcT LINK project, initiated through the 'Nanoscience through Engineering to Application' programme. The project aims to provide a direct contribution to the global safety assessment of nanomaterials described by the OECD Working Party on Manufactured Nanomaterials (WPMN). The LINK project will develop essential and seminal test methods and data on two agreed nanomaterials that are of particular commercial relevance to the UK. The project will innovate the scientific foundations for adapting or creating test methods that enable the ecotoxicological hazard assessment of nanomaterials. Both particles (i.e. CeO2 and ZnO) are part of a list of 14 nanomaterials, identified as commercially relevant to the global economic impact of nanotechnology. Furthermore, the development of methods to characterize CeO2 and ZnO nanomaterials in concert with parallel and coordinated development for other nanomaterials across the OECD testing program will enablethe future establishment of QSARs (Quantitative Structure Activity Relationships) for predictive safety evaluations of novel nanomaterials.The resulting scientific advancement will help to secure an economic future for the commercialisation of nanotechnologies in and by the UK and provide crucial UK leadership and information to the OECD's global programme on nanomaterials safety assessment.

拟议的研究构成了Prospect Link项目不可或缺的一部分，该项目是通过“通过工程到应用程序的纳米科学”计划启动的。该项目旨在为经合组织制造的纳米材料（WPMN）所描述的纳米材料的全球安全评估提供直接贡献。链接项目将开发与英国特别商业相关性的两种商定纳米材料的基本测试方法和数据。该项目将创新用于适应或创建测试方法的科学基础，以使生态毒理学危害评估纳米材料。这两个粒子（即CEO2和ZnO）都是14个纳米材料列表的一部分，被确定为与纳米技术的全球经济影响在商业上相关。此外，在经合组织测试计划中，与其他纳米材料的平行和协调开发一起表征CEO2和ZnO纳米材料的方法的开发将使未来的QSARS建立（定量结构活动关系）（定量结构活动关系）通过对新的纳米材料进行预测性的安全性，以确保纳米材料的预测安全性。英国并为OECD关于纳米材料安全评估的全球计划提供至关重要的领导和信息。