MORTALITY BY RACE AMONG LOW BIRTH WEIGHT INFANTS

低出生体重婴儿的种族死亡率

• 批准号: 3324597
• 负责人: ROBERT MICHIELUTTE
• 金额: $ 17.84万
• 依托单位: WAKE FOREST UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-07-01 至 1991-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3324597
• 关键词: African American; caucasian American; disease /disorder proneness /risk; epidemiology; gestational age; health care service utilization; infant mortality; mother /infant health care; patient /disease registry; premature infant human; vital statistics

The primary goal of the proposed study is to examine the relationship between race and infant mortality in the context of a general model of risk factors for infant mortality. Data on births and deaths will be obtained from a 20 county region in North Carolina (Perinatal Care Region Two) for 1984-1987. The model will include demographic characteristics, medical and behavioral factors, and characteristics of the mother and infant previously found to be related to low birth weight and infant mortality. Analyses that focus specifically on low birth weight births also will include a risk factor defined as medical etiology that identifies the proximal processes and events judged directly responsible for a preterm birth, and incorporates them into a more detailed categorization of the traditional dichotomization of term vs. preterm birth. Detailed preliminary analyses will be conducted between race and medical etiology and the manner in which they related to infant mortality. Data on medical etiology will be obtained from records of hospitals in Perinatal Care Region Two, and from a small number of hospitals peripheral to the region where residents may go to give birth. These data will be merged with computerized information from the North Carolina vital statistics birth/fetal death and birth/infant death files, and with data from the prevention of prematurity program currently being conducted in Perinatal Care Region Two. Data from the prevention of prematurity program will provide an expanded set of risk factors generally not available in studies of risk for infant mortality. As the initial step in the development of multivariate models of risk for infant mortality, all risk factors hypothesized to impact on infant mortality will be identified as exogenous and intervening. Intervening variables will be further delineated in terms of their type and temporal proximity to the outcome variable. Multivariate analyses will examine the appropriateness of a single model of risk for infant mortality as opposed to separate models for specific subgroups of women. Analyses will be conducted separately for neonatal and postneonatal deaths.

拟议研究的主要目标是审查 种族与婴儿死亡率之间的关系 婴儿死亡危险因素的一般模式。 出生数据 将从北部20个县地区获得死亡人数 1984 - 1987年，卡罗莱纳（第二围产期护理区）。 模型 将包括人口统计学特征、医疗和行为 因素和母亲和婴儿的特点，以前 发现与低出生体重和婴儿死亡率有关。 特别关注低出生体重儿的分析也 将包括定义为医学病因学的风险因素， 识别直接判断的最近过程和事件 负责早产，并将其纳入一个 对传统的二分法进行更详细的分类， 足月与早产。 详细的初步分析将在 进行种族和医学病因学之间的方式， 这与婴儿死亡率有关。 医学病因学数据将从以下记录中获得： 第二围产期护理区的医院， 居民可能去的地区周边的医院 生孩子 这些数据将与计算机化的 来自北卡罗来纳州出生/胎儿生命统计的信息 死亡和出生/婴儿死亡档案，以及 目前正在进行的预防早产计划， 围产期护理区2。 数据来自预防 早产儿计划将提供一套扩大的风险因素 在婴儿死亡风险的研究中通常没有。 作为多变量模型开发的第一步， 婴儿死亡风险，所有风险因素假设影响 对婴儿死亡率的影响将被确定为外源性的， 干预。 干预变量将在 术语的类型和与结果的时间接近度 变量 多变量分析将检查 婴儿死亡风险的单一模型， 针对特定女性亚群的单独模型。 分析将 新生儿和新生儿后期死亡分别进行。