ORGANIZING THE HGI--SOCIAL IMPACT AND TECHNOLOGY DESIGN

组织 HGI——社会影响和技术设计

• 批准号: 3333605
• 负责人: STEPHEN HILGARTNER
• 金额: $ 4.86万
• 依托单位: COLUMBIA UNIV NEW YORK MORNINGSIDE
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-06-14 至 1995-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3333605
• 关键词: comprehensive medical planning; decision making; ethics; genome; health /scientific organization; health science research analysis /evaluation; human genetic material tag; informatics; politics; sociology /anthropology; technology /technique

DESCRIPTION (Investigator's Abstract): The initiative to map and sequence the human genome is entering a critical period. For the next five years, the genomics community will focus on developing technology and organizational structures for accomplishing its goal of obtaining the complete sequence by the year 2005. The choices made in the early 1990s will define the basic outline of the technological system for mapping and sequencing the human genome and lay a new groundwork for twenty first century biology and biotechnology. The social impacts of the design and implementation of the genome project are likely to be enormous. Decisions made today about the technological and organizational structure of the genome project will affect how the information the project produces is eventually used and the social impact of that information. Similarly, decisions about how to manage the tensions inherent in scientific collaboration on this scale are likely to have an effect on research ethics well beyond the genomics community. The next five years are thus a strategic research opportunity of exceptional importance for understanding the evolution of the genome project and its impact. The proposed study will explore how the agenda for research, for organizational design, and for policy of the genomics community takes shape during this critical period. The system/network approach to technology, and the concept of agenda-setting, provide a theoretical framework. The research will use a prospective, longitudinal study of a cohort of key informants from the community, in-depth interviewing, and participant observation in carefully selected laboratories.

描述（研究者摘要）：绘制和排序的主动性 人类基因组正在进入关键时期。 未来五年， 基因组学界将专注于开发技术和 实现其目标的组织结构 2005 年完成序列。 20 世纪 90 年代初做出的选择 明确测绘技术体系基本框架 对人类基因组进行测序并为二十一世纪奠定新的基础 世纪生物学和生物技术。 设计和社会影响 基因组计划的实施可能是巨大的。 决定 今天关于技术和组织结构 基因组计划将影响该项目产生的信息的方式 最终使用以及该信息的社会影响。 相似地， 关于如何管理科学中固有的紧张局势的决定 这种规模的合作可能会对研究伦理产生影响 远远超出了基因组学界。 因此，未来五年是 对理解具有特殊重要意义的战略研究机会 基因组计划的演变及其影响。 拟议的研究 将探讨研究议程、组织设计和 因为基因组学界的政策是在这一关键时期形成的 时期。 系统/网络技术方法以及概念 议程设置，提供理论框架。 该研究将使用一个 对一组关键知情人进行的前瞻性、纵向研究 深入社区、深入访谈、认真参与观察 选定的实验室。