ULTRASONIC EVALUATION IN DIRECT ARTERIAL SURGERY

直接动脉手术中的超声评估

• 批准号: 3336303
• 负责人: DONALD E STRANDNESS
• 金额: $ 37.03万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-09-08 至 1991-09-07
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3336303
• 关键词: aorta; artery stenosis; atherosclerosis; cardiovascular disorder diagnosis; carotid artery; computer assisted instruction; disease /disorder proneness /risk; early diagnosis; endarterectomy; human subject; longitudinal human study; noninvasive diagnosis; online computer; pathologic process; peripheral blood vessel disorder; stroke; ultrasound blood flow measurement

It is well recognized that atherosclerosis is a major medical problem which involves major arteries supplying the heart, the brain and the extremities. It has been possible with the development of ultrasonic techniques to evaluate the location and extent of the involvement in the carotid and peripheral arteries. Since the method is noninvasive, painless and safe, it has been possible to utilize the combination of pulse echo and Doppler methods to assess the degree of narrowing at the time of the examination and to follow changes in the disease during follow-up. It is proposed to further develop these methods to employ the use of computerized pattern recognition which will permit quantification of information present in the Doppler spectrum to predict the degree of stenosis. In addition to providing a more objective assessment of the degree of stenosis, the ultrasonic duplex method will be used to assess the prevalence of restenosis after carotid endarterectomy and its relevance to the development of clinical events such as transient ischemic attacks and strokes.

众所周知，动脉粥样硬化是一个主要的医学问题， 涉及到供应心脏、大脑和 四肢。随着超声波的发展，使之成为可能。 评估参与的位置和程度的技术 颈动脉和外周动脉。由于该方法是无创的，无痛的 而且安全的，已经可以利用脉冲回波和 多普勒法评估冠脉狭窄的程度 检查并跟踪随访期间疾病的变化。它是 建议进一步发展这些方法，使用计算机化的 一种模式识别，它将允许对存在的信息进行量化 在多普勒频谱中预测狭窄程度。除了……之外 为了更客观地评估狭窄程度， 将使用超声双工法评估患病率 颈动脉内膜剥脱术后再狭窄及其与预后的关系 临床事件，如短暂性脑缺血发作和 中风。