CORONARY RISK FACTOR REDUCTION IN CHILDHOOD

减少儿童时期的冠心病危险因素

• 批准号: 3336664
• 负责人: HEATHER J WALTER
• 金额: $ 52.06万
• 依托单位: INSTITUTE FOR CANCER PREVENTION
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-08-01 至 1988-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3336664
• 关键词: adolescence (12-20); behavioral medicine; cardiovascular disorder education; cardiovascular disorder epidemiology; cardiovascular disorder prevention; chronic disease /disorder; coronary disorder; curriculum; diet; disease /disorder proneness /risk; education evaluation /planning; human subject; hypercholesterolemia; hypertension; longitudinal human study; middle childhood (6-11); nutrition education; nutrition related tag; obesity; pediatrics; physical fitness; psychobiology; secondary schools; tobacco abuse education

Our goal is to reduce the risk for the future development of coronary heart disease (CHD) through the favorable modification of risk factor distributions among a population of school children. The primary objective is to evaluate, over a three year period, the degree of maintenance of the previously demonstrated effectiveness of a school-based program known as "Know Your Body" (KYB). The specific aims are to reduce the prevalence and incidence of cigarette smoking; and to favorably shift the population distributions of blood pressure, blood lipid levels, body mass indices and cardiovascular fitness. The study will continue to follow longitudinally a population of school children previously participating (Grades four through nine) in a randomly assigned, controlled intervention study. The "Know Your Body" program was shown to favorably modify the distributions of blood pressure, blood lipid levels and cigarette smoking study, subjects participating in the previous study will be tracked for three more years (Grades ten through twelve) to determine the extent to which the favorable outcomes previously demonstrated are maintained or increased over time after cessation of intervention. Investigations also will be conducted to determine the differential maintenance of effect among various sub-groups of the population. In addition, analyses conducted with control group data will permit investigation of the physiological, genetic and psychosocial determinants of CHD risk factors. Products of the proposed study will be original, evaluated CHD prevention curriculum materials for school grades four through six.

我们的目标是降低冠心病未来发展的风险 疾病(CHD)通过对危险因素的有利修饰 在一群学童中的分布。首要目标是 是在三年的时间里评估 此前证明了以学校为本的计划的有效性，该计划被称为 《了解你的身体》(KYB)。具体目标是降低患病率和 吸烟的发生率；并有利地转移人口 血压、血脂水平、体重指数和体重指数的分布 心血管健康。这项研究将继续纵向跟踪 以前参加过的学童人数(四年级至四年级 9)在随机分配的对照干预研究中。“知情者” “你的身体”计划被证明有利于改变血液的分布 研究对象：血压、血脂水平和吸烟 参与前一项研究的人将再被跟踪三年 (从10级到12级)来确定有利的程度 以前证明的结果会随着时间的推移而保持或增加 在停止干预之后。还将进行调查，以 确定不同子组之间的差异化效果保持 人口中的一部分。此外，使用控制组数据进行的分析 将允许对生理、遗传和心理社会进行调查 冠心病危险因素的决定因素。拟议研究的产品将是 学校年级原创、经评估的冠心病预防课程材料 四个到六个。