CORONARY RISK FACTOR REDUCTION IN CHILDHOOD

减少儿童时期的冠心病危险因素

• 批准号: 3336665
• 负责人: HEATHER J WALTER
• 金额: $ 43.37万
• 依托单位: INSTITUTE FOR CANCER PREVENTION
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-08-01 至 1988-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3336665
• 关键词: adolescence (12-20); behavioral medicine; cardiovascular disorder education; cardiovascular disorder epidemiology; cardiovascular disorder prevention; chronic disease /disorder; coronary disorder; curriculum; diet; disease /disorder proneness /risk; education evaluation /planning; human subject; hypercholesterolemia; hypertension; longitudinal human study; middle childhood (6-11); nutrition education; nutrition related tag; obesity; pediatrics; physical fitness; psychobiology; secondary schools; tobacco abuse education

Our goal is to reduce the risk for the future development of coronary heart disease (CHD) through the favorable modification of risk factor distributions among a population of school children. The primary objective is to evaluate, over a three year period, the degree of maintenance of the previously demonstrated effectiveness of a school-based program known as "Know Your Body" (KYB). The specific aims are to reduce the prevalence and incidence of cigarette smoking; and to favorably shift the population distributions of blood pressure, blood lipid levels, body mass indices and cardiovascular fitness. The study will continue to follow longitudinally a population of school children previously participating (Grades four through nine) in a randomly assigned, controlled intervention study. The "Know Your Body" program was shown to favorably modify the distributions of blood pressure, blood lipid levels and cigarette smoking study, subjects participating in the previous study will be tracked for three more years (Grades ten through twelve) to determine the extent to which the favorable outcomes previously demonstrated are maintained or increased over time after cessation of intervention. Investigations also will be conducted to determine the differential maintenance of effect among various sub-groups of the population. In addition, analyses conducted with control group data will permit investigation of the physiological, genetic and psychosocial determinants of CHD risk factors. Products of the proposed study will be original, evaluated CHD prevention curriculum materials for school grades four through six.

我们的目标是降低冠心病的风险 通过对危险因素的有利修改， 在学龄儿童群体中的分布。 主要目的 是在三年的时间里，评估 以前证明的有效性，以学校为基础的计划， “了解你的身体”（KYB）。 具体目标是降低发病率， 吸烟的发生率;并有利地转移人口 血压、血脂水平、体重指数和 心血管健康 本研究将继续纵向跟踪a 以前参加的学龄儿童人数（四年级至 9）在一项随机分配的对照干预研究中。 “知” 你的身体”计划被证明有利于修改血液的分布 血压、血脂水平和吸烟研究，受试者 参与先前研究的人将被跟踪三年以上 （10 - 12级），以确定在何种程度上， 先前证明的结果随着时间的推移而保持或增加 停止干预后。 还将进行调查， 确定不同亚组之间的差异维持效应 的人口。 此外，还对对照组数据进行了分析 将允许调查的生理，遗传和心理社会 冠心病危险因素的决定因素。 拟议研究的产品将是 原始的，经过评估的学校年级冠心病预防课程材料 四到六个