CORONARY ARTERY SURGERY STUDY

冠状动脉手术研究（卡斯）是一项多中心， 在780例患者中比较药物和手术治疗的随机试验 患有轻度或中度心绞痛的患者，或 心肌梗死后无症状。 卡斯注册 人群由24，959名患有冠心病的患者组成 动脉造影检查疑似缺血性冠状动脉疾病 15个医疗中心。 卡斯登记研究患者 在1974年到1979年之间注册。 合格登记研究患者 1975年至1979年间参加了随机试验。 所有 登记的患者随访至1982年。 继续跟进- 目前正在每年进行症状和生命状态的检查， 随机试验中780例患者和1319例患者的联系人 符合随机化条件但不符合 参加了试验 对其他人的生命状态进行随访 登记患者通过国家死亡指数完成。 继续向卡斯协调中心提供合同资金， 跟踪、数据分析和编写研究报告， 登记和随机试验于1988年6月结束。 卡斯 调查人员建议继续随访， 5年，并继续开展卡斯调查员的活动， 利用广泛的卡斯数据库进行各种研究 协议.

The Coronary Artery Surgery Study (CASS) is a multicenter, randomized trial comparing medical and surgical therapy in 780 patients who had mild or moderate angina, or who were asymptomatic after myocardial infarction. The CASS registry population consists of 24,959 patients who had coronary arteriography for suspected ischemic coronary disease at the fifteen participating medical centers. CASS registry patients were enrolled between 1974 and 1979. Eligible registry patients were enrolled in the randomized trial between 1975 and 1979. All registry patients were followed through 1982. Continued follow- up for symptoms and vital status is currently being done by annual contact for the 780 patients in the randomized trial and the 1319 patients who were eligible for randomization but were not enrolled in the trial. Follow-up for vital status for the other registry patients is done through the National Death Index. Contract funds to the CASS Coordinating Center for continued follow-up, data analysis, and preparation of research reports from the registry and randomized trial end in June of 1988. The CASS investigators are proposing to continue follow-up for an additional 5 years and to continue the activity of the CASS investigators in using the extensive CASS data bank for a variety of research protocols.