HUMAN RESPONSES TO FOUR COOLING BLANKET TEMPERATURES

退烧药和低温毯用于治疗身体抬高 温度 两者都被临床证明是相对有效的 单独或组合使用。 低温治疗温度设定指南 毯子稀缺且冲突。 使用的低温毯温度 降低体温的范围一般从38华氏度（3.3度 C）至85华氏度（29.4摄氏度）或更高。 在自动模式下，大多数 低温设备将毯子冷却到40华氏度 (4.4在大多数冷却处理期间。 需要 极低的包层温度尚未得到证实。 此外，本发明还 寒冷的温度对患者来说是不舒服的， 身体的防御反应与颤抖，保存热量，因此， 抵消了治疗目标。 温度更高，其他冷却方式 媒体，已被证明产生身体冷却。 本研究探讨的 冷却效果，并比较四种冷却的相对不适 毯子温度结合使用退烧药， 受试者发烧。 120名受试者将平均分配 通过将起始温度随机化为四个毯温度， 45华氏度（7.2摄氏度），55华氏度（12.8摄氏度）， 65华氏度（18.3摄氏度）、75华氏度（23.9摄氏度）。 受试者 在每一组将检查的时间长度，以达到所需的 体温、秋后、颤抖和不适。 此项研究将提供 为制定使用低温毯的明确指南提供数据 使用退烧药。

Antipyretics and hypothermia blankets are used to treat elevated body temperature. Both have been shown clinically to be relatively effective alone or in combination. Guidelines for temperature setting of hypothermia blankets are scarce and conflicing. Hypothermia blanket temperatures used to reduce body temperature generally range from 38 degrees F (3.3 degrees C) to 85 degrees F (29.4 degrees C) or higher. In the automatic mode, most hypothermia equipment cools the blanket to a temperature of 40 degrees F (4.4 degrees C) during most of the cooling treatment. The need for extremely low blanket temperatures has not been demonstrated. Further, cold temperatures are uncomfortable for the patient and stimulate the body's defenses to react with shivering which conserves heat, thus counteracting the therapeutic goal. Warmer temperatures with other cooling media, have been shown to produce body cooling. This study examines the cooling effects and compares the relative discomfort of four cooling blanket temperatures in combination with the use of antipyretics on subjects with fever. One hundred twenty subjects will be assigned equally by randomization by starting temperature into the four blanket temperature groups, 45 degrees F (7.2 degrees C), 55 degrees F (12.8 degrees C), 65\degrees F (18.3 degrees C), 75 degrees F (23.9 degrees C). The subjects in each group will be examined for length of time to reach a desired temperature, after-fall, shivering and discomfort. The study will provide data for developing clear guidelines for the use of hypothermia blankets with the use of antipyretics.