HUMAN RESPONSES TO FOUR COOLING BLANKET TEMPERATURES

退烧药和降温毯用于治疗身体抬高 温度。两者都已被临床证明是相对有效的 单独的或混合的。体温过低的体温设定指南 毛毯稀缺且相互冲突。使用的低温毯子温度 降低体温一般在华氏38度(3.3度)之间 C)至85华氏度(29.4摄氏度)或更高。在自动模式下，大多数 降温设备将毯子冷却到40华氏度 (4.4摄氏度)在大部分冷却处理期间。需要 极低的毯子温度还没有被证明。此外， 寒冷的温度使患者感到不适，并刺激 身体的防御反应是颤抖，这可以保存热量，因此 抵消了治疗目标。通过其他降温使温度变暖 媒体，已经被证明能产生身体降温。这项研究考察了 降温效果及比较四种降温方式的相对不适性 毯子温度结合退烧药的使用 发烧的受试者。120名受试者将被平均分配 按随机化按起始温度分为四个毯子温度 分组，45华氏度(7.2摄氏度)，55华氏度(12.8摄氏度)， 华氏65度(18.3摄氏度)，华氏75度(23.9摄氏度)。主题 将在每组中检查一段时间以达到所需的 气温、秋后感、颤抖和不适。这项研究将提供 制定使用低温毯子的明确指南的数据 退烧药的使用。

Antipyretics and hypothermia blankets are used to treat elevated body temperature. Both have been shown clinically to be relatively effective alone or in combination. Guidelines for temperature setting of hypothermia blankets are scarce and conflicing. Hypothermia blanket temperatures used to reduce body temperature generally range from 38 degrees F (3.3 degrees C) to 85 degrees F (29.4 degrees C) or higher. In the automatic mode, most hypothermia equipment cools the blanket to a temperature of 40 degrees F (4.4 degrees C) during most of the cooling treatment. The need for extremely low blanket temperatures has not been demonstrated. Further, cold temperatures are uncomfortable for the patient and stimulate the body's defenses to react with shivering which conserves heat, thus counteracting the therapeutic goal. Warmer temperatures with other cooling media, have been shown to produce body cooling. This study examines the cooling effects and compares the relative discomfort of four cooling blanket temperatures in combination with the use of antipyretics on subjects with fever. One hundred twenty subjects will be assigned equally by randomization by starting temperature into the four blanket temperature groups, 45 degrees F (7.2 degrees C), 55 degrees F (12.8 degrees C), 65\degrees F (18.3 degrees C), 75 degrees F (23.9 degrees C). The subjects in each group will be examined for length of time to reach a desired temperature, after-fall, shivering and discomfort. The study will provide data for developing clear guidelines for the use of hypothermia blankets with the use of antipyretics.