课题基金 / 基金详情

Small Grant for Visiting Researcher Professor Marek Kimmel, Rice University

Small Grant for Visiting Researcher Professor Marek Kimmel, Rice University
为莱斯大学客座研究员 Marek Kimmel 教授提供小额资助
批准号:
EP/J006653/1
负责人:
David Rand
金额:
$3.05万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2011
资助国家:
英国
项目状态:
已结题
起止时间:
2011 至 --

项目摘要

项目成果

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中文摘要
翻译
系统生物学(SB)旨在了解整个生物系统的运作,更重视组件之间的相互作用以及此类相互作用的后果,而不是分子组件本身。因此,数学建模和统计分析是关键的理论工具。这项工作被认为是非常重要的,以更好地了解一个非常广泛的生物和医学的优先事项,如疾病机制,药物发现,药物靶点验证,园艺和农业。Kimmel博士是三个领域的国际领先专家,这三个领域是这项研究的核心:分支过程(特别是细胞生物学和遗传学的理论和应用);遗传学和基因组学的统计方面;以及细胞信号系统的数学建模。这笔赠款是资助四个半月的访问沃里克大学,以相互加强在这些领域的研究,并鼓励在博士Kimmel的小组研究人员之间的新合作,并在沃里克和其他地方的研究人员在系统生物学或数学/统计技能的兴趣,以促进它。
英文摘要
Systems Biology (SB) seeks to understand the workings of biological systems as a whole, placing a greater emphasis on the interactions between components, and the consequences of such interactions, than on the molecular components themselves. As such mathematical modelling and statistical analysis are key theoretical tools. Such work is considered to be of great importance to a better understanding of an enormously broad range of biological and medical priorities such as disease mechanisms, pharmaceutical drug discovery, drug target validation, and horticulture and agriculture. Dr Kimmel is an internationally leading expert in three areas which are central to this research: branching processes (particularly theory and applications in cell biology and genetics); statistical aspects of genetics and genomics; and mathematical modelling of cellular signaling systems. This grant is to fund a visit of four and a half months to the University of Warwick to mutually strengthen research in these areas and to encourage new collaborations between researchers at Dr Kimmel's group, and researchers at Warwick and elsewhere with interests in Systems Biology or the mathematical/statistical skills to contribute to it.
期刊论文(3)
专著(0)
科研奖励(0)
会议论文
Modeling Neutral Evolution Using an Infinite-Allele Markov Branching Process
使用无限等位基因马尔可夫分支过程模拟中性进化
DOI: 10.1155/2013/963831
发表时间: 2013
期刊: International Journal of Stochastic Analysis
影响因子: --
作者: [Wu X]
通讯作者: Wu X
DOI: 10.1371/journal.pone.0093396
发表时间: 2014
期刊: PloS one
影响因子: 3.7
作者: [Bertolusso R, Tian B, Zhao Y, Vergara L, Sabree A, Iwanaszko M, Lipniacki T, Brasier AR, Kimmel M]
通讯作者: Kimmel M
Using catastrophes, dynamics & data analysis to uncover how differentiating cells make decisions
  • 批准号:
    EP/T031573/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $56.87万
  • 财政年份:
    2021
  • 负责人:
    David Rand
  • 依托单位:
Collaborative Research: From Brains to Society: Neural Underpinnings of Collective Behaviors Via Massive Data and Experiments
Collaborative Research: From Brains to Society: Neural Underpinnings of Collective Behaviors Via Massive Data and Experiments
  • 批准号:
    1939934
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $39.83万
  • 财政年份:
    2019
  • 负责人:
    David Rand
  • 依托单位:
Mathematical Foundations of Information and Decisions in Dynamic Cell Signalling
  • 批准号:
    EP/P019811/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $45.39万
  • 财政年份:
    2017
  • 负责人:
    David Rand
  • 依托单位:
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