EPIDEMIOLOGY OF NEWLY DIGNOSED PSYCHOTIC DISORDERS

这项研究涉及的分布，效度和时间稳定性 首次入院患者的诊断，一年内的病程模式 两年期，以及预后效用和诊断特异度 特别是一套临床和心理社会指标 病前功能、药物滥用、自杀行为和治疗 经历。在目前的赠款下，我们成立了合作社 与Long Suffolk县的35家门诊和住院机构达成协议 小岛。在每个设施中，一名联络员筛选所有入院人员，以便 推荐首次入院的精神病患者参加我们的项目。设计 需要基线、6个月和24个月的全面诊断和 心理社会评估，以及与参与者的持续接触 每3个月一次。通过项目建立共识诊断 精神病学家在基线上，和一个纵向派生的最佳估计 在6个月和24个月的评估后确定诊断。 最初的拨款被批准为期3年，以证明 建立网络的可行性并确定实际 符合条件的患者数量。我们现在预计，招生阶段将 招募600名病人的工作将於一九九四年完成。在.期间 在前16.5个月的现场工作中，182名患者接受了基线治疗 采访。前56个月的六个月最佳估计诊断 患者表示，最常见的诊断是双相情感障碍。 (27%)，其次是精神分裂症(21%)，精神病性抑郁症(13%)，以及 分裂情感障碍(13%)。此外，56名患者中有46%的人 终生滥用药物或依赖的标准。在.期间 更新期间，我们将完成现场和分析阶段的 学习。我们还计划在24小时后与样本保持联系 一个月的访谈，为未来的研究做准备。

The study addresses the distribution, validity and temporal stability of diagnosis in first-admission patients, patterns of illness course over a two-year period, and the prognostic utility and diagnostic specificity of a set of clinical and psychosocial indicators, in particular premorbid functioning, substance abuse, suicidal behavior, and treatment experiences. Under the current grant, we established cooperative agreements with 35 in- and outpatient facilities in Suffolk County, Long Island. In each facility, a liaison screens all admissions in order to refer first-admission psychotic patients to our project. The design entails a baseline, 6- and 24- month comprehensive diagnostic and psychosocial assessment, as well as continual contact with participants every 3 months. A consensus diagnosis is established by project psychiatrists at baseline, and a longitudinally-derived best-estimate diagnosis is determined after the 6- and 24-month assessments. The original funding was approved for 3 years to demonstrate the feasibility of establishing the network and to determine the actual numbers of eligible patients. We now anticipate that the intake phase to recruit a sample of 600 patients will be completed by 1994. During the first 16.5 months of field work, 182 patients were administered baseline interviews. Six-month best estimate diagnoses available for the first 56 patients indicate that the most common diagnosis is bipolar disorder (27%), followed by schizophrenia (21%), psychotic depression (13%), and schizoaffective disorder (13%). In addition, 46% of the 56 patients met criteria for a lifetime substance abuse or dependence. During the renewal period, we will complete the field and analytic phases of the study. We also plan to maintain contact with the sample beyond the 24 month interview to prepare for future research.