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PSYCHOSOCIAL FACTORS IN SUDDEN CARDIAC DEATH

心源性猝死的心理社会因素

基本信息

批准号：
3391970
负责人：
SUE A THOMAS
金额：
$ 10.97万
依托单位：
LIFE CARE HEALTH FOUNDATION
依托单位国家：
美国
项目类别：
财政年份：
1990
资助国家：
美国
起止时间：
1990-05-02 至 1993-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/3391970
关键词：
anxiety behavioral medicine cardiovascular disorder epidemiology depression disease /disorder proneness /risk human morbidity human mortality human subject longitudinal human study myocardial infarction psychological stressor psychometrics psychophysiology questionnaires social support network sudden cardiac death type A /type B personality

项目摘要

Sudden cardiac death (SCD) is one of the major public health problems facing western society, and it is the leading cause of mortality in the U.S. This proposal constitutes an independent project complimentary to the ongoing NIH clinical trial "Cardiac Arrhythmia Suppression Trial (CAST)". The CAST protocol is designed to examine the effectiveness of antiarrhythmic drug therapy at improving survival among post-myocardial infarction patients with ventricular arrhythmias. This proposal is designed to examine the contributions of social psychological, and behavioral factors to survival in these patients. A number of social and psychological variables have been related to morbidity or mortality from cardiovascular diseases. The independent contributions and interrelationships among these psychosocial and physiological risk factors for SCD mortality will be examined. It is assumed that physiological status will be more strongly related to survival than psychosocial variables, but the addition of psychosocial variables will make significant additional contributions to the explanation of length of survival. All patients who are participating in 8 CAST sites (n=800) will be asked to participate in this study. CAST inclusion criteria are designed to limit participation to a population with high risk for SCD but without medical complications which would preclude or complicate drug therapy. Each subject will complete psychosocial questionnaires at baseline and every 4 months during follow-up visits for two years. This study will provide the basis for identification of a subgroup of post myocardial infarction patients whose psychosocial status promotes susceptibility to SCD. Nurses play a major therapeutic role in the identification and management of these patients and can provide the interventions necessary to improve survival.

心源性猝死（SCD）是我国主要的公共卫生问题之一西方社会面临的问题，这是主要原因，在美国的死亡率。这一建议构成了一个独立的该项目是对正在进行的NIH临床试验“心脏”的补充心律失常抑制试验（CAST）"。 CAST协议是旨在检验抗疟疾药物的有效性提高心肌梗死后患者生存率的治疗室性心律失常患者。该提案旨在研究社会心理学的贡献，行为因素对这些患者生存的影响。一些社会和心理变量与发病率有关或心血管疾病的死亡率。独立这些社会心理因素和将检查SCD死亡率的生理危险因素。它假设生理状态将与比心理社会变量更能影响生存，心理社会变量将产生显着的额外影响对解释生存期长短的贡献。参加8个CAST研究中心的所有患者（n=800）将被要求参加这项研究。 CAST入选标准为旨在将参与限制在高风险人群中， SCD，但无可能妨碍或复杂的药物治疗。每名受试者将完成心理社会学基线时和随访期间每4个月进行一次问卷调查访问了两年。这项研究将为确定一个亚组提供依据心肌梗死后患者的心理社会状况增加对SCD的易感性。护士在治疗中扮演着重要的角色在这些患者的识别和管理中发挥作用，提供必要的干预措施以提高生存率。