ESCAPE BEHAVIOR INTEGRATION AND PLASTICITY

这项研究的目的是帮助我们了解 负责学习和反应选择的神经元机制 复杂的综合行为系统 这些相关问题将在一个相对简单的系统中进行研究， 小龙虾的侧向巨大逃逸反应回路， 各种形式的控制和调节。 行为，电生理和解剖学研究建议在 (1)致敏、长时程增强的细胞基础， 联想学习，（2）参与的调节回路， 将外侧巨大逃逸整合到 动物，和（3）神经活动对突触形成的影响， 损伤后再生。

The purpose of this research is to contribute to our understanding of the neuronal machinery responsible for learning and response selection in complex, integrated behavioral repertoires. These related problems are to be studied in a relatively simple system, the lateral giant escape reaction circuit of the crayfish, which is subject to a variety of forms of control and modulation. Behavioral, electrophysiological, and anatomical research is proposed on (1) the cellular basis of sensitization, long-term potentiation, and associative learning, (2) modulatory circuitry that is involved in integrating lateral giant escape into the behavioral repertoire of the animal, and (3) effects of neural activity on synapse formation during regeneration following injury.