MOLECULAR PATHOLOGY OF ALZHEIMER PAIRED HELICAL FILAMENT

阿尔茨海默病配对螺旋丝的分子病理学

• 批准号: 3400307
• 负责人: DENNIS J SELKOE
• 金额: $ 9.62万
• 依托单位: MCLEAN HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1983
• 资助国家: 美国
• 起止时间: 1983-12-01 至 1985-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3400307
• 关键词: Alzheimer's disease; affinity chromatography; aging; brain cell; chemical cleavage; covalent bond; crosslink; electron microscopy; high performance liquid chromatography; histochemistry /cytochemistry; hybridomas; hydrolysis; immunochemistry; microscopy; molecular pathology; monoclonal antibody; neuroanatomy; neurochemistry; neurofibrillary tangles; organelles; peptidases; radionuclide double label

项目成果

Electron microscopic localization of Alzheimer neurofibrillary tangle components recognized by an antiserum to paired helical filaments.

抗血清识别的阿尔茨海默氏症神经原纤维缠结成分的电子显微镜定位与成对的螺旋丝。

• DOI: 10.1097/00005072-198603000-00006
• 发表时间: 1986
• 期刊: Journal of neuropathology and experimental neurology
• 影响因子: 3.2
• 作者: Perry,G;Selkoe,DJ;Block,BR;Stewart,D;Autilio-Gambetti,L;Gambetti,P
• 通讯作者: Gambetti,P