INTERNATIONAL SYMPOSIUM ON THE BIOLOGY OF HEMATOPOIESIS

国际造血生物学研讨会

• 批准号: 3434605
• 负责人: Nicholas Dainiak
• 金额: $ 1.9万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-06-01 至 1990-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3434605
• 关键词: blood; hematopoiesis; travel

This proposal requests funds for an international conference on the biology of hematopoiesis. The Symposium will comprehensively review recent developments at the cellular and molecular levels in the field of hematopoietic stem cell differentiation and growth. Our specific aim is to gather and attract a group of over 200 scientists who are of international repute or who are in the formative years of their careers as scientists in the field for the purpose of presenting, discussing and exchanging scientific information relative to hematopoietic stem cells. Our goal is to encourage the free exchange of conceptual and technical information regarding newly developed cell culture, biochemical, and molecular genetic techniques. Our hope is that potentially fertile areas of basic and clinical research may be identified in order to accelerate the application of laboratory findings to the bedside as it relates to derangements of hematopoiesis. The proceedings of this conference will be published in a timely fashion with the hope of stimulating continued development of this field. The symposium will provide a multidisciplinary approach to the field of hematopoiesis. It is scheduled to take place over a full five-day period and to address the following areas: (1) tissue culture systems and cellular requirements for hematopoietic differentiation; (2) growth factor receptors and molecular and cell biology of hematopoiesis, including cell surface receptors for growth factors, post-receptor events and DNA structural modifications during differentiation; (3) gene therapy, including regulation of gene expression, gene transfer, in vivo models of gene therapy and the future of human gene therapy; (4) hematopoietic growth factors, including recombinant and naturally occurring, endogenous growth factors; and (5) radiation injury to bone marrow stem cells and in vivo effects of purified hematopoietic growth factors. In addition to workshops, poster sessions will provide the opportunity for young investigators to present data pertaining to each of these topics. Our longterm objective is to review and explore new approaches to understanding the cell biology of hematopoiesis.

这项提案要求为召开一次关于下列问题的国际会议提供资金： 造血生物学。 研讨会将全面 回顾细胞和分子水平的最新进展， 造血干细胞分化和生长领域。 我们的具体目标是聚集和吸引超过200名 科学家谁是国际知名的或谁是在 他们作为科学家在该领域的职业生涯的形成期， 介绍、讨论和交流科学知识的目的 造血干细胞相关信息。 我们的目标是 鼓励概念和技术信息的自由交流 关于新开发的细胞培养、生物化学和分子生物学， 基因技术 我们的希望是， 可以确定基础和临床研究，以便 加速实验室结果在临床上的应用 因为它与造血功能紊乱有关。 诉讼 本次会议的成果将及时公布， 希望能促进这一领域的持续发展。 研讨会将提供一个多学科的方法， 造血领域。 它计划在一个完整的 五天的时间，并解决以下几个方面：（1）组织 造血干细胞的培养系统和细胞要求 分化;（2）生长因子受体与分子和细胞 造血生物学，包括细胞表面受体 生长因子、受体后事件和DNA结构 分化过程中的修饰;（3）基因治疗，包括 基因表达调控，基因转移，体内模型， 基因治疗和人类基因治疗的未来;（4） 造血生长因子，包括重组的和天然的 发生，内源性生长因子;和（5）辐射损伤， 骨髓干细胞和纯化的骨髓干细胞在体内的作用 造血生长因子 除了研讨会，海报 会议将为年轻的研究人员提供机会， 提供与每个主题有关的数据。 我们的长期 目的是审查和探索新的方法来了解 造血的细胞生物学