NEUROLOGICAL/NEUROPSYCHOLOGICAL ASPECTS OF HIV INFECTION

HIV 感染的神经学/神经心理学方面

• 批准号: 3436123
• 负责人: ROBERT M LEVY
• 金额: $ 2.5万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-04-01 至 1990-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3436123
• 关键词: AIDS; AIDS /HIV test; human immunodeficiency virus 1; meeting /conference /symposium; nervous system disorder; neuropsychology

Infection with the human immunodeficiency virus (HIV-1) results not only in immunologic dysfunction but also in neurological and neuropsychological illness. Ten percent of all patients with the acquired immunodeficiency syndrome (AIDS) have a neurological complaint as their first sign of illness, 37% of AIDS patients have significant neurological dysfunction during their lifetime and 75% have neuropathological abnormalities on autopsy. Neuropsychological abnormalities have been reported in 8% to 67% of patients with AIDS and in 10% to 40% of people with HIV-1 infection. Neurological illness arises not only as a result of opportunistic processes but also as a result of primary HIV-1 infection of the nervous system. Thus, the large number of people infected with HIV-1 are also at risk of developing neurological or neuropsychological illness, even in the absence of immunological dysfunction or systemic illness. Since the first reports of HIV-1-related neurological illness in 1983, research into the neurological and neuropsychological complications of AIDS and HIV-1 infection has provided a number of new insights into the mechanisms and clinical manifestations of HIV-1 infection of the nervous system. The goal of Neurological and Neuropsychological Aspects of HIV Infection, a satellite meeting of the Vth World Conference on AIDS, is to bring together the world's experts in various aspects of HIV infection and its neurological and neuropsychological complications. These experts will first provide an overview course on the neurological complications of AIDS and HIV Infection. This course will be followed by a meeting during which several plenary talks will review the most important recent results of research in this area. Finally, during open scientific sessions, researchers from around the world will be able to share the results of their research in this field and have a forum for the discussion of this research. This international scientific meeting should result in an increased awareness of the neurological and neuropsychological aspects of AIDS and HIV infection; this increased awareness should result in improved care of patients with HIV infection as well as directing and coordinating future research into this critical area.

人类免疫缺陷病毒（HIV-1）感染结果 不仅影响免疫功能障碍，还影响神经系统和神经系统功能障碍。 神经心理疾病。 所有患者的百分之十 获得性免疫缺陷综合症（艾滋病）具有神经系统疾病 37% 的艾滋病患者将主诉作为其患病的第一个征兆 其一生中存在显着的神经功能障碍，并且 75% 尸检有神经病理学异常。 据报道，8% 至 67% 的患者存在神经心理异常 艾滋病患者和 10% 至 40% 的 HIV-1 感染者 感染。 神经系统疾病的发生不仅是由于 机会主义过程，也是原发性 HIV-1 的结果 神经系统感染。 于是，大量的人 感染 HIV-1 的人也有患神经系统疾病或 神经心理疾病，即使没有免疫学 功能障碍或全身性疾病。 自从首次报道 HIV-1 相关神经系统疾病以来 1983年，研究神经病学和神经心理学 艾滋病和 HIV-1 感染的并发症提供了许多 对该病的机制和临床表现有了新的认识 HIV-1 神经系统感染。 神经内科的目标 和艾滋病毒感染的神经心理学方面，卫星 第五届世界艾滋病大会的会议 世界各地艾滋病毒感染及其相关方面的专家 神经系统和神经心理学并发症。 这些专家 首先将提供神经学概述课程 艾滋病和艾滋病毒感染的并发症。 本课程将是 随后举行一次会议，期间将举行几次全体会议 回顾该领域最近最重要的研究成果。 最后，在公开科学会议期间，来自各地的研究人员 世界将能够分享他们的研究成果 该领域并有一个讨论该研究的论坛。 这次国际科学会议应该会导致更多 对神经学和神经心理学方面的认识 艾滋病和艾滋病毒感染；这种认识的提高应该会导致 改善对艾滋病毒感染者的护理以及指导 并协调这一关键领域的未来研究。