NEUROLOGICAL/NEUROPSYCHOLOGICAL ASPECTS OF HIV INFECTION

感染人类免疫缺陷病毒(HIV-1)结果 不仅在免疫功能障碍方面，而且在神经学和 神经心理疾病。10%的患者患有这种疾病 获得性免疫缺陷综合征(AIDS)有一种神经系统 抱怨是他们疾病的第一个症状，37%的艾滋病患者 在他们的一生中有显著的神经功能障碍，75% 尸检有神经病理异常。 据报道，有8%到67%的人有神经心理异常 艾滋病患者和10%至40%的HIV-1感染者 感染。神经系统疾病的出现不仅仅是因为 机会主义的过程，但也是最初的HIV-1的结果 神经系统的感染。因此，大量的人 感染HIV-1的人也有患上神经性或 神经心理疾病，即使在缺乏免疫学的情况下 功能障碍或全身性疾病 自#年首次报告HIV-1相关神经疾病以来 1983年，对神经学和神经心理学的研究 艾滋病和HIV-1感染的并发症提供了一些 对心力衰竭发病机制和临床表现的新认识 神经系统感染HIV-1病毒。神经学的目标 艾滋病毒感染的神经心理学方面，一个卫星 第五届世界艾滋病大会的会议，是为了将 世界上在艾滋病毒感染及其各个方面的专家 神经学和神经心理学的并发症。这些专家 我将首先提供一个神经学概述课程 艾滋病和艾滋病毒感染的并发症。这门课程将是 随后举行了一次会议，期间将举行几次全体会谈 回顾该领域最重要的最新研究成果。 最后，在公开的科学会议期间，来自世界各地的研究人员 世界将能够分享他们的研究成果 并为这一领域的研究提供了一个论坛进行讨论。 这次国际科学会议应该会带来更多 对神经学和神经心理学方面的认识 艾滋病和艾滋病毒感染；这一提高认识应导致 改善对艾滋病毒感染患者的护理，并指导 并协调未来对这一关键领域的研究。

Infection with the human immunodeficiency virus (HIV-1) results not only in immunologic dysfunction but also in neurological and neuropsychological illness. Ten percent of all patients with the acquired immunodeficiency syndrome (AIDS) have a neurological complaint as their first sign of illness, 37% of AIDS patients have significant neurological dysfunction during their lifetime and 75% have neuropathological abnormalities on autopsy. Neuropsychological abnormalities have been reported in 8% to 67% of patients with AIDS and in 10% to 40% of people with HIV-1 infection. Neurological illness arises not only as a result of opportunistic processes but also as a result of primary HIV-1 infection of the nervous system. Thus, the large number of people infected with HIV-1 are also at risk of developing neurological or neuropsychological illness, even in the absence of immunological dysfunction or systemic illness. Since the first reports of HIV-1-related neurological illness in 1983, research into the neurological and neuropsychological complications of AIDS and HIV-1 infection has provided a number of new insights into the mechanisms and clinical manifestations of HIV-1 infection of the nervous system. The goal of Neurological and Neuropsychological Aspects of HIV Infection, a satellite meeting of the Vth World Conference on AIDS, is to bring together the world's experts in various aspects of HIV infection and its neurological and neuropsychological complications. These experts will first provide an overview course on the neurological complications of AIDS and HIV Infection. This course will be followed by a meeting during which several plenary talks will review the most important recent results of research in this area. Finally, during open scientific sessions, researchers from around the world will be able to share the results of their research in this field and have a forum for the discussion of this research. This international scientific meeting should result in an increased awareness of the neurological and neuropsychological aspects of AIDS and HIV infection; this increased awareness should result in improved care of patients with HIV infection as well as directing and coordinating future research into this critical area.