RESTING METABOLIC RATE IN CHILDHOOD OBESITY

儿童肥胖的静息代谢率

• 批准号: 3428630
• 负责人: DAVID E SCHOTTE
• 金额: $ 3.27万
• 依托单位: ROSALIND FRANKLIN UNIV OF MEDICINE & SCI
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-07-01 至 1988-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3428630
• 关键词: basal metabolism; bioenergetics; body physical characteristic; calorimetry; case history; caucasian American; child physical development; human subject; male; middle childhood (6-11); obesity; parent offspring interaction

The aim of the proposed study is to extend previous research on the energy expenditure of children at risk for obesity. In particular, it is hypothesized that deficits in resting metabolic rate (RMR) may exist among the biological children of obese parents and that these deficits may predispose the child to obesity. The subjects will be male, Caucasian children between the ages of 9 and 10, and their parents. Groups will include normal weight children of normal weight parents, obese children of normal weight parents, normal weight children of obese parents, and obese children of obese parents. Anthropometric measurement data will be obtained on both the children and their parents; demographic and weight history data will be collected from the parents. In addition, standard indirect calorimetry procedures will be employed to obtain data on the resting metabolic rates of the children in the four groups. Deficits in energy expenditure among lean children at risk for obesity and among obese children of obese parents who are currently in the dynamic phase of obesity may account for the observed familial patterns of obesity. The results of this study may also serve to identify potential target groups for both primary prevention and early intervention strategies with children.

这项研究的目的是扩展以前的研究， 有肥胖风险的儿童的能量消耗 在 特别是，假设静息代谢缺陷 肥胖的生物学儿童中可能存在RMR 父母，这些缺陷可能会使孩子 肥胖 受试者将是年龄在 9和10，还有他们的父母。 组将包括正常体重 父母体重正常的儿童，父母体重正常的肥胖儿童， 肥胖父母的正常体重子女，以及 肥胖父母的肥胖孩子 人体测量 将获得儿童及其父母的数据; 人口统计学和体重历史数据将从 父母 此外，标准的间接量热程序 将被用来获得数据的休息代谢率 四个组的孩子。 有肥胖风险的瘦弱儿童的能量消耗不足 肥胖和肥胖儿童的肥胖父母谁是 目前处于动态阶段的肥胖可能占 观察肥胖的家族模式。 本研究结果 也可以用来确定潜在的目标群体， 初级预防和早期干预战略， 孩子