MOLECULAR GENETIC STUDIES OF EIKENELLA CORRODENS

腐蚀艾克内拉的分子遗传学研究

• 批准号: 3436836
• 负责人: Rona L. Hirschberg
• 金额: $ 10.8万
• 依托单位: UNIVERSITY OF MISSOURI KANSAS CITY
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-06-01 至 1993-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3436836
• 关键词: Neisseriaceae; bacterial antigens; bacterial genetics; bacterial proteins; cell components; electron microscopy; genetic strain; microorganism growth; molecular genetics; monoclonal antibody; mutant; pilus

DESCRIPTION: (Adapted from applicant's abstract) The author proposes to study Eikenella corrodens, a bacterial pathogen associated with a variety of infections. Almost nothing is known about the molecular genetics and pathogenicity of the microorganism. A colonial dimorphism exhibited by the bacteria could be important in determining virulence. The author will focus efforts on defining the basis of the colonial variation using biochemical, immunological and molecular genetic techniques.

描述：(改编自申请人的摘要)作者建议 研究腐蚀性艾肯氏菌，一种与多种细菌有关的病原体 感染的可能性。对分子遗传学几乎一无所知 微生物的致病性。一种殖民二形性，表现为 细菌在确定毒力方面可能很重要。作者将 集中努力确定殖民变异的基础，使用 生物化学、免疫学和分子遗传学技术。

项目成果

Scanning electron microscopy of Eikenella corrodens colony morphology variants.

Eikenella Corrodens 菌落形态变异的扫描电子显微镜。

• DOI: 10.1111/j.1600-0765.1994.tb01242.x
• 发表时间: 1994
• 期刊: Journal of periodontal research
• 影响因子: 3.5
• 作者: Cobb,CM;Helber,JT;Hirschberg,R
• 通讯作者: Hirschberg,R