1993 GORDON RESEARCH CONFERENCE ON WOUND REPAIR

这份申请的目的是为一个新的戈登寻求支持 创伤修复研究会议。 这个的整体设计 最近，戈登研究会议批准了 咨询委员会和会议目前定于6月13日至18日， 1993. 创伤修复领域经历了一个快速发展的阶段， 现代化，面对最近的发现， 细胞内信号传导和细胞基质相互作用。 在过去五 多年来，我们见证了国家和国际 致力于这一主题的社会和不断扩大的文献， 纪律 虽然一些研讨会召开，以解决主题， 伤口修复，戈登研究会议提供了一个独特的， 交流最新信息的亲密气氛， 这种现象的生物学。创伤修复既是一个临床难题 和生物学科。 这是一个过程， 止血和炎症通过形成一个临时的 以纤维增生和血管生成为特征的肉芽组织， 愈合的伤口或疤痕。 病程中出现明显的病理变化 创伤修复一方面包括广泛的纤维化， 另一方面是各种形式的溃疡。 伤口修复几乎不是一个 局限于皮肤领域，但最常在 使用皮肤损伤的实验模型。 其他专门机构和 组织在修复主题上显示出重要的变化， 在最广泛的伤口修复背景下考虑。 这次会议是 最初设想于1990年，希望将基本的 科学家、临床科学家和工业界形成一种非正式的 可以围绕最先进的讲座核心优化联系。 会议，概述，将处理可溶性和不溶性 修复过程的介质，组织中的专门修复过程 如骨、肺和肝，过度纤维增生的控制， 不愈合伤口的生物学基础 星期四的特别会议 会议的晚上将致力于一个更历史的观点， 在过去四十年中发展起来的再生概念。 这次会议的目的是，特别是鼓励人们不 直接参与伤口修复的领域，因为重要的 间接利益 需要考虑的重要领域包括 生长因子和淋巴因子作用的机制， 基质生物合成和干细胞群的性质 参与各种器官的伤口愈合。 本次大会是 预计将有120至130名与会者， 学术界、政府和工业界。 创伤修复是一个复杂的生物学过程 现象 治疗方式，即使使用最先进的 分子的方法，将不会成功，除非更密切的联系， 伤口的生物学真实性和 参与的细胞群。 戈登研究会议， 这是一个重要的机会， 讨论伤口修复的生物学。

The purpose of this application is to seek support for a new Gordon Research Conference on Wound Repair. The overall design of this conference was recently approved by the Gordon Research Conference advisory board and the meeting is presently scheduled for June 13 - 18, 1993. The field of wound repair has undergone a rapid phase of modernization in the face of recent discoveries in the area of intracellular signaling and cell matrix interactions. In the last five years, we have witnessed the formation of national and international societies devoted to this topic and an expanding literature in the discipline. While a number of symposia convene to address topics in wound repair, the Gordon Research Conference provides a unique and intimate atmosphere for the exchange of state-of-the-art information on the biology of this phenomenon . Wound repair is both a clinical problem and a biological discipline. It is a process which proceeds from hemostasis and inflammation through the formation of a temporary granulation tissue characterized by fibroplasia and angiogenesis, to a healed wound or scar. Obvious pathological changes during the course of wound repair include, on the one hand extensive fibrosis, and on the other hand various forms of ulceration. Wound repair is hardly a process confined to the cutaneous domain, but is most frequently studied in experimental models using skin lesions. Other specialized organs and tissues show important variations on the repair theme and need to be considered in the broadest context of wound repair. This conference was initially conceived in 1990 with the hope of bringing together basic scientists, clinical scientists and industry into a form where informal contacts could be optimized around a core of state-of-the-art lectures. The conference, as outlined, will deal with soluble and insoluble mediators of the repair process, specialized repair processes in tissues such as bone, lung, and liver, the control of excess fibroplasia, and the biological basis of nonhealing wounds. A special session on Thursday evening of the conference will be devoted a more historical view of the concepts of regeneration that have developed over the last four decades. This conference is designed, in particular, to encourage persons not directly involved in wound repair to the area because of important collateral interests. Important areas to be considered include mechanisms of growth factor and lymphokine action, the regulation of matrix biosynthesis, and the nature of stem cell populations participating in wound healing in various organs. This conference is expected to have, 120 to 130 attendees, with balanced participation from academia, government and industry. Wound repair is a complex biological phenomenon. Treatment modalities, even using the most sophisticated molecular approaches, will not succeed unless a closer connection is made between the biological reality of the wound and the biochemical behavior of participating cell populations. The Gordon Research Conference, represents an important opportunity to create an ongoing venue for discussions on the biology of wound repair.