THIRD AND FOURTH INTERNATIONAL CHROMOSOME 11 WORKSHOPS

这一赠款申请要求资金支持第三和 第四届11号染色体国际研讨会， 旨在汇集各大实验室进行大规模 关于人类染色体的全球测绘项目， 人类特定疾病基因的遗传作图和分离 11号染色体。 第三届人类11号染色体国际研讨会 将于1992年9月14日至16日在加州圣地亚哥举行。 的 第四次国际讲习班将于9月在英国伦敦举行 在1993年。 这些会议是在第一次和第二次非常成功的 年在马里兰州贝塞斯达举行的11号染色体国际研讨会 1989年和1991年分别在法国巴黎举行。 会议将汇集100名 来自美国、加拿大、欧洲和 日本将讨论基因组研究的最新进展、新战略和技术 测绘，并促进信息和资源的交流。 的 会议的具体目标是：1）使调查人员能够 介绍11号染色体物理和遗传图谱的最新数据，2） 允许综合共识地图，并在可能的情况下， 收集测绘数据，3）讨论和促进生产和使用 11号染色体社区的共同资源，4）收集 在一个共同的数据库中映射数据，以及5）规划战略， 完成这一测绘项目。 具体计划和进展情况 联合筛选YAC文库中的11号染色体特异性克隆， 分发参考图书馆及收集资料 在GDB中，我们将讨论。 基因组数据库的代表，以及 物理和遗传绘图工作组、信息学和自动化 工作组，将被邀请强调这个社区的互动 与他人 与以往的研讨会一样，本次研讨会的成果将 发表在Genomics或American Journal of Human Genetics上。 第三届国际研讨会的组织者将是彼得·利特尔 （帝国学院，伦敦）和格伦埃文斯（索尔克研究所）。 组织者 第四届国际研讨会将在第三届 国际研讨会，但无疑将包括第三届会议的组织者， 国际讲习班。

This grant application requests funds for the support of the Third and Fourth International Workshops on Chromosome 11, meetings which are designed to bring together major laboratories carrying out large scale global mapping projects on this human chromosome, and those groups working on the genetic mapping and isolation of specific disease genes on human chromosome 11. The third International Workshop on Human Chromosome 11 will be held in San Diego California, September 14 through 16, 1992. The fourth International Workshop will be held in London, England, in September of 1993. These meetings follow the highly successful First and Second International Workshops on Chromosome 11 held in Bethesda, Maryland, in 1989, and in Paris, France, in 1991. The meeting will bring together 100 investigators from laboratories in the United States, Canada, Europe and Japan to discuss recent progress, new strategies and technology for genome mapping, and to facilitate exchange of information and resources. The specific goals of the meeting will be to: 1) allow investigators to present recent data on physical and genetic mapping of chromosome 11, 2) allow synthesis of consensus maps and, wherever possible, facilitate joint collection of mapping data, 3) discuss and promote the production and use of common resources for the chromosome 11 community, 4) collection of the mapping data in a common database, and 5) planning strategies for eventual completion of this mapping project. Specific plans and progress on the joint screening of YAC libraries for chromosome 11-specific clones, distribution of reference libraries and collection of data to be included in GDB will be discussed. Representatives of the Genome Database, and physical and genetic mapping working groups, informatics and automation working groups, will be invited to emphasize interaction of this community with others. As with previous workshops, the results of this workshop will be published in Genomics or in the American Journal of Human Genetics. Organizers of the Third International Workshop will be Peter Little (Imperial College, London) and Glen Evans (Salk Institute). Organizers of the Fourth International Workshop will be determined at the Third International Workshop but will undoubtedly include organizers of the Third International Workshop.