PROMPT SEPSIS : Partnership for Rapid On-site Microfluidic POC Test for Sepsis

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The University of Liverpool (UoL) has identified a combination of 3 biomarkers which provide good discrimination of sepsisin febrile children. MicroLab Devices (MLD), Forsite Diagnostics (FD) and UoL have combined their technology to developan innovative point-of-care (POC) diagnostic system combining microfluidic and lateral flow technology to provide adisposable, zero energy platform for measuring this combination of sepsis markers. The project will refine the POC systemfor the introduction of raw saliva or blood samples directly into the system and validate the device using clinical samples tocreate a diagnostic algorithm to guide decision making. The innovation lies in the novel combination of biomarkers AND thecombined platform technologies that provide a new diagnostic system to allow the detection of sepsis rapidly and cheaply.The test has the potential to reduce delays in diagnosis and unnecessary admissions to hospital and the platform has thepotential to impact across the whole POC market.