TOOTH WEAR AND TOOTH USE IN CERCOPITHECUS AETHIOPS

埃塞俄比亚鹿的牙齿磨损和牙齿使用

• 批准号: 3447121
• 负责人: MARK F TEAFORD
• 金额: $ 5.4万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-04-01 至 1988-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3447121
• 关键词: biological models; bite strength; dietary constituent; growth /development; longitudinal animal study

This is a longitudinal study of tooth wear using a nonhuman primate model. Two groups of animals (green monkeys or vervets) are to be used in this study and they are already being raised on different diets for a study of craniofacial growth and masticatory function at the Case Western Reserve University School of Dentistry. Baseline data (e.g., dental impressions, SEM micrographs) have already been collected through an NIH post-doctoral fellowship. Dental impressions will continue to be taken at six-week intervals, and the resultant replicas will be used in quantitative scanning electron microscope analyses of dental microwear and stereophotogrammetric analyses of the overall rate and form of tooth wear in these animals. Microscopic and macroscopic changes in shearing crest, cusp, and basin morphology will be measured. The two major questions to be asked in this study are: how does tooth wear occur at the microscopic and macroscopic levels, and how does tooth use change through time as tooth wear progresses? Three lines of evidence will provide answers to these questions: (1) interrelationships between the measured microscopic and macroscopic wear features, (2) comparisons between the different dietary groups, and (3) information on craniofacial growth, bite force, and bone strain being collected through the C.W.R.U. School of Dentistry study. The results of this quantitative longitudinal study will bring a much clearer perspective to the question of the functional significance of primate tooth morphology. This study also benefits by being able to correlate the changes in tooth wear with the changing shape of the craniofacial region as indicated by a variety of measurements taken from the face and skull of the same animal subjects.

这是一项使用非人灵长类动物模型对牙齿磨损进行的纵向研究。 将使用两组动物(绿色猴子或马鞭草)进行这项活动 他们已经被用不同的饮食喂养以进行一项研究 凯斯西部保护区的头面部发育和咀嚼功能 大学牙科学院。基线数据(例如，牙齿印模， 扫描电子显微镜照片)已经通过NIH博士后收集 团契。六周后将继续进行牙科印模 间隔，生成的复本将用于定量扫描 牙齿微磨损的电子显微镜分析和立体摄影测量 对这些动物牙齿磨损的总体比率和形式进行分析。 剪切峰、尖、盆的微观和宏观变化 形态将被测量。在这个过程中要问的两个主要问题 研究内容有：牙齿磨损是如何在微观和宏观上发生的 水平，以及牙齿使用量如何随时间的变化而变化 有进展吗？以下三条证据将为这些问题提供答案 问题：(1)测量的显微镜和 宏观磨损特征，(2)不同膳食之间的比较 以及(3)有关颅面生长、咬合力和骨骼的信息 菌株是通过C.W.R.U牙科研究学院收集的。这个 这一定量纵向研究的结果将带来一个更加清晰的 透视灵长类牙齿的功能意义问题 形态学。这项研究还受益于能够将 牙齿磨损随颅面区域形状变化的变化 从面部和头骨进行的各种测量表明 同样的动物实验对象。