Internally lit photobioreactors for enhanced product formation from algae using LED systems: Energy transformed into high value chemical products

使用 LED 系统增强藻类产品形成的内部照明光生物反应器：将能量转化为高价值化学产品

• 批准号: EP/L022389/1
• 负责人: Robert Lovitt
• 金额: $ 37.8万
• 依托单位: Swansea University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2014
• 资助国家: 英国
• 起止时间: 2014 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FL022389%2F1
• 关键词: Internally; lit; photobioreactors; enhanced; product

Algae are an incredibly diverse group of organisms that are becoming increasing important of economically and scientific interest the potential providing efficient low carbon processes that will not compete for food production or land use. However, large scale processes using these organisms are hamstrung by the requirement to use natural light which although it is free is unpredictable in intensity, quality and periodicity being dependent weather conditions. Natural light also restricts potential photobioreactor (PBR) geometries, raceways and tubular PBR's making large scale operation problematic, unreliable reducing the productivity of these systems. Internally lit PBR's could revolutionise these with the intensive production of high quality, high value algae and open up the field to exploitation using the tools of synthetic biology to develop the safe productive capacity these systems. The project therefore aims to investigate internally lit PBR's. This is multidisciplinary collaboration of biologists, physicists and engineers. We will design, construct and test internally lit PBRs have substantially higher productivity and capability over conventionally natural lit systems. On the face on it, the investment and cost of internally lit PBR's are much higher than natural lit systems, however, this can more than compensated by the potential advantages and benefits of growing and manipulating algae in highly controlled lighting environments. This includes more efficient use of light that is provided by LED's which has narrow spectra and easily controlled intensity reducing the cost of production. The sophisticated use of LED lighting also offers up exciting opportunities to control and monitor biochemical composition and product formation much of which is influenced by the quality and intensity of light. With internal lighting reactors can also be scaled in three dimensions and are independent of natural light. Reactors can be tailored and optimised for different products and simplified the strategies for the development of genetically engineered algae can be safely implemented. The project will focus on the testing of novel flexible PBR design to realise the potential of this approach. The work consists of 5 work packages (i) The development of new methods of selection and use of LED's. (ii) The development of lighting plates where LED's will be mounted internally of light weight lighting plates within the reactor that also facilitating good heat and mass transfer. Lighting control systems will also be developed to minimise energy consumption while allowing efficient growth and product formation of algae. (iii) The PBR systems will be designed an operated at 1 m3 scale which will be sufficient scale to allow easy scale of these systems (iv) The reactor will constructed, commission and characterised. (v) These internally lit PBR concepts will be centred on high value product formation and will be tested and evaluated with Heamotoccus pluvalis for the production of cells and astaxanthin.

藻类是一类极其多样化的生物体，在经济和科学利益方面正变得越来越重要，能够提供高效的低碳过程，而不会竞争粮食生产或土地使用。然而，使用这些生物体的大规模过程受到使用自然光的要求的阻碍，尽管自然光是免费的，但在强度、质量和周期性方面是不可预测的，这取决于天气条件。自然光还限制了潜在的光生物反应器(PBR)的几何结构、沟槽和管状PBR，使大规模操作成为问题，不可靠，降低了这些系统的生产率。内部照明的PBR可以通过密集生产高质量、高价值的藻类来彻底改变这些系统，并利用合成生物学工具开放该领域以开发这些系统的安全生产能力。因此，该项目的目标是研究内部发光的PBR。这是生物学家、物理学家和工程师的多学科合作。我们将设计、建造和测试内部照明PBR，与传统的自然照明系统相比，内部照明PBR具有更高的生产率和能力。从表面上看，内部照明PBR的投资和成本比自然照明系统高得多，然而，在高度受控的照明环境中种植和操纵藻类的潜在优势和好处足以弥补这一点。这包括更有效地利用LED提供的光，LED具有窄光谱和易于控制的强度，降低了生产成本。LED照明的复杂使用也提供了令人兴奋的机会来控制和监测生化成分和产品的形成，其中很大程度上受到光的质量和强度的影响。有了内部照明，反应堆也可以进行三维缩放，并且不受自然光的影响。反应堆可以针对不同的产品进行量身定做和优化，简化了基因工程藻类开发的战略，可以安全地实施。该项目将专注于测试新型灵活的PBR设计，以实现这一方法的潜力。这项工作包括5个工作包：(I)开发选择和使用LED的新方法。(Ii)开发照明板，其中LED将安装在反应堆内的轻质照明板的内部，这也有助于良好的热量和质量传递。还将开发照明控制系统，以最大限度地减少能源消耗，同时允许藻类高效生长和产品形成。(Iii)PBR系统将以1立方米的规模设计和运行，该规模将足以使这些系统易于规模。(Iv)反应堆将建造、调试和表征。(V)这些内部点亮的PBR概念将集中在高价值产品的形成上，并将与Heamotoccus plvalis进行测试和评估，以生产细胞和虾青素。