Circuit, cellular and synaptic mechanisms of nucleus accumbens deep brain stimulation

伏隔核深部脑刺激的电路、细胞和突触机制

• 批准号: nhmrc : GNT1160472
• 金额: $ 64.29万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/circuit-cellular-synaptic-brain-stimulation/1379131
• 关键词: Circuit; cellular; synaptic; mechanisms; nucleus

Deep brain stimulation has immense potential to help patients with brain-based disorders that fail to benefit from all other treatments. To ensure this potential is realised, we must understand how it works. This project will determine how brain stimulation changes the way information is transmitted in a part of the brain that regulates responses to negative and positive events. This information is necessary to help improve brain stimulation treatments and clinical outcomes for patients.

脑深部刺激具有巨大的潜力，可以帮助那些无法从所有其他治疗中受益的脑部疾病患者。为了确保实现这一潜力，我们必须了解它是如何运作的。这个项目将确定大脑刺激如何改变信息在大脑中调节对消极和积极事件的反应的部分的传输方式。这些信息是必要的，以帮助改善脑刺激治疗和患者的临床结果。