CANCER SURVIVING ADOLESCENTS REDUCING RISK BEHAVIORS

描述：（改编自申请人摘要）有36，000个 美国儿童癌症的长期幸存者。 器官 妥协和肿瘤发生可能是由于多模式的晚期效应， 为这些幸存者提供治疗。 当务之急是让这些青少年幸存者 质疑吸烟和饮酒的决定，因为潜在的晚 影响（纤维化肺损伤、心肌功能障碍和肝损伤）。 关于癌症幸存青少年的危险行为的研究已经 有限，没有研究将质量决策与这些风险联系起来， 迄今尚未对这一领域的干预措施进行研究。 基于导频 对青少年幸存者的研究，目前饮酒的流行率（40%） 值得进一步研究，因为它略高于国家 图. 在本研究中，质量决策技能显著 与风险行为相关;随着决策技能的提高，风险 行为减少。 这项研究的主要目的是增加 长期癌症幸存青少年的高质量决策技能， 减少吸烟和饮酒的冒险行为。 第一阶段将是一项横断面描述性研究（两年和四年）， 月时间框架）。 数据将通过以下方式收集：a）半结构化 对青少年幸存者进行访谈; B）对父母进行邮寄调查;以及 （c）对年龄相匹配的同龄人进行家庭访谈。 第二阶段将使用调查结果 从第1阶段开始，制定健康促进计划，以降低风险 吸烟和饮酒的行为，一个专门针对 这些青少年幸存者的需求。 该计划将整合：a） 生存、青春期和养育子女的具体信息; B） 具有价值澄清的决策技能，c）建模;以及d） 社会抚养费 第二阶段还将包括一个前测试后测试随机 临床试验与相同的幸存者和他们的父母;随访将 包括在1个月、6个月和12个月时对幸存者进行重复测量， 父母六个月。 拒绝临床试验的幸存者将被 比较，使用从临床记录中提取的特征， 参加这个项目的人。

DESCRIPTION: (Adapted from applicant's abstract) There are 36,000 long-term survivors of childhood cancer in the United States. Organ compromise and oncogenesis may result from late effects of multi-modal treatments for these survivors. It is imperative that these teen survivors question the decision to smoke and to consume alcohol due to potential late effects (fibrotic lung damage and myocardial dysfunction and liver damage). Studies of risk behaviors of cancer-surviving adolescents have been limited, no studies have linked quality decision making to these risks, and intervention in this area has not been studied to date. Based on a pilot study of teen survivors, the prevalence of current alcohol use (4O percent) warrants further study since it was slightly higher than the national figure. In this study, quality decision-making skills significantly correlated with risk behaviors; as decision-making skills increased, risk behaviors decreased. The major objective for this study is to increase quality decision-making skills in long-term cancer-surviving teens in order to decrease risk-taking behaviors of smoking and alcohol consumption. Phase I will be a cross-sectional descriptive study (two years and four months timeframe). Data will be collected by: a) semi-structured interviews for teen survivors; b) a mailed survey approach for parents; and c) home interviews for age-matched peers. Phase II will use the findings from Phase 1 to develop a health promotional program to reduce the risk behaviors of smoking and alcohol use, a program tailored specifically to the needs of these adolescent survivors. The program will integrate: a) information specific to survivorship, adolescence, and parenting; b) decision-making skills with values clarification, c) modeling; and d) social support. Phase II will also include a pre-test post-test randomized clinical trial with the same survivors and their parents; follow-up will involve repeated measures at one, six, and twelve months for survivors and six months for parents. Survivors who refuse the clinical trial will be compared, using characteristics drawn from clinical records, to survivors who participate in the program.