Clarifying Shared and Unique Neurocognitive Processes across Depression and Dementia

阐明抑郁症和痴呆症的共同和独特的神经认知过程

• 批准号: nhmrc : GNT1168313
• 金额: $ 8.85万
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/clarifying-shared-unique-depression-dementia/1379455
• 关键词: Clarifying; Shared; Unique; Neurocognitive; Processes

Depressive features in late-life frequently co-occur with cognitive decline, but are often treated by clinicians as distinct. Despite this, depressive symptoms increase the risk of dementia, suggesting a degree of overlap in illness trajectories. This project will apply novel analytic methods to clarify neurobiological predictors of cognitive decline in those with depression, and quantify common and unique brain-based biomarkers across those with established depression and dementia.

晚年的抑郁特征经常与认知能力下降同时发生，但临床医生通常将其视为不同的。尽管如此，抑郁症状会增加痴呆症的风险，这表明疾病轨迹有一定程度的重叠。该项目将应用新的分析方法来阐明抑郁症患者认知能力下降的神经生物学预测因子，并量化抑郁症和痴呆症患者常见和独特的脑生物标志物。