Clinical and biological markers of disease presentation and progression in early frontotemporal dementia

早期额颞叶痴呆疾病表现和进展的临床和生物学标志物

• 批准号: nhmrc : 510106
• 负责人: Dr Laurie Miller
• 金额: $ 33.85万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/clinical-biological-markers-frontotemporal-dementia/98175
• 关键词: Clinical; biological; markers; disease; presentation

Frontotemporal dementia accounts for 12-20% of all dementia cases and is as common as Alzheimer's disease in the < 65 year olds. Our understanding of this disease remains limited. This project aims to better characterise the range and progression of deficits in early frontotemporal dementia using tests of brain function and magnetic resonance imaging. This will assist in better diagnosis of these patients and, ultimately, may be used to monitor the outcomes of therapeutic interventions.

额颞叶痴呆症占所有痴呆症病例的12%-20%，在65岁的老年人中与阿尔茨海默病一样常见。我们对这种疾病的了解仍然有限。该项目旨在通过脑功能和磁共振成像的测试，更好地描述早期额颞叶痴呆的缺陷范围和进展。这将有助于更好地诊断这些患者，并最终可能被用于监测治疗干预的结果。