Clinical effectiveness of aspirin in healing chronic venous leg ulcers: a randomised double-blinded placebo-controlled trial

阿司匹林治疗慢性腿部静脉溃疡的临床疗效：一项随机双盲安慰剂对照试验

• 批准号: nhmrc : 1069329
• 负责人: A/Pr Anna Barker
• 金额: $ 52.81万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/clinical-effectiveness-aspirin-controlled-trial/455388
• 关键词: Clinical; effectiveness; aspirin; healing; chronic

Chronic venous leg ulcers (VLU) are a common and costly problem. People with chronic wounds found on the ankles and legs can be spontaneous or occur after minor trauma, they are often painful and ooze fluid. The burden is expected to rise with an ageing population and growing epidemic of diabetes and obesity which will increase challenges for clinicians. We will perform a clinical trial to see if aspirin plus 3 layer compression in people with venous leg ulcers heal more quickly.

慢性下肢静脉溃疡（VLU）是一种常见且昂贵的问题。在脚踝和腿部发现慢性伤口的人可能是自发的，也可能是在轻微创伤后发生的，他们通常会感到疼痛并渗出液体。随着人口老龄化以及糖尿病和肥胖症的日益流行，预计负担将增加，这将增加临床医生的挑战。我们将进行一项临床试验，看看是否阿司匹林加3层压缩的人与静脉腿部溃疡愈合更快。