The ASPREE-fracture sub-study: Does daily low-dose aspirin reduce fracture risk in healthy older adults?

老年人骨折造成的残疾、死亡率和医疗负担是一个日益严重的世界性问题。尽管数十年的临床研究、最佳实践指南和旨在降低骨折风险的治疗方法都取得了进展。世界卫生组织已将预防骨折确定为公共卫生的优先事项。这项研究将确定一种广泛可用、简单和廉价的健康干预措施——阿司匹林——是否能减少澳大利亚老年人骨折和相关残疾的发生率。

Disability, mortality and healthcare burden from fractures in older people is a growing problem worldwide. This is despite decades of clinical research, best practice guidelines and advances in therapies that aim to reduce fracture risk. The World Health Organization has identified fracture prevention as a public health priority. This study will determine whether a widely available, simple and inexpensive health intervention—aspirin—can reduce the incidence of fracture and associated disability amongst older Australians.