PROTECTIVE TREATMENT FOR CATHETERS
PROTECTIVE TREATMENT FOR CATHETERS
导管的保护性处理
批准号：
3500953
负责人：
JOHN B NEWKIRK
金额：
$5.0万
依托单位国家：
美国
项目类别：
财政年份：
1987
资助国家：
美国
项目状态：
已结题
起止时间：
1987-08-01 至 1988-04-14
中文摘要
翻译
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英文摘要
Long Term Objective:
To make commercially available central venous catheters (CVC)
which have been chemically treated to reduce their tendency to
induce infections thereby bringing major humanitarian benefits
and substantial reductions in hospital care costs.
Specific Aims and Methodology:
(1) apply an already developed process for antimicrobial
protection of silicone rubber to a commonly used CVC (Hickman)
device;
(2) determine the duration and levels of antimicrobial activity of
optimally treated catheters during perfusion with saline,
nutritional, and oncotherapeutic solutions;
(3) determine the degrees of protection of treated catheters
against lumen colonization in vitro, by methods used in (2) above;
(4) determine the biocompatibility in mouse tissue of the treated
catheter material;
(5) determine the effects of normal storage on antibacterial
activity and tensile strength of treated catheters.
期刊论文(12)
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LateTIME: a phase-II, randomized, double-blinded, placebo-controlled, pilot trial evaluating the safety and effect of administration of bone marrow mononuclear cells 2 to 3 weeks after acute myocardial infarction.
LateTIME：一项 II 期、随机、双盲、安慰剂对照试点试验，评估急性心肌梗塞后 2 至 3 周给予骨髓单核细胞的安全性和效果。
LateTIME：一项 II 期、随机、双盲、安慰剂对照试点试验，评估急性心肌梗塞后 2 至 3 周给予骨髓单核细胞的安全性和效果。
DOI：
--
发表时间：
2010
期刊：
Texas Heart Institute journal
影响因子：
0.9
作者：
[Traverse,JayH, Henry,TimothyD, Vaughan,DouglasE, Ellis,StephenG, Pepine,CarlJ, Willerson,JamesT, Zhao,DavidXM, Simpson,LaraM, Penn,MarcS, Byrne,BarryJ, Perin,EmersonC, Gee,AdrianP, Hatzopoulos,AntonisK, McKenna,DavidH, Forder,]
通讯作者：
Forder,
DOI：
10.1007/s11883-013-0341-9
发表时间：
2013-08
期刊：
Current atherosclerosis reports
影响因子：
5.8
作者：
[Szady AD, Pepine CJ, Sharma SV, Cogle CR, Perin EC, Ellis SG, Moyé LA, Cardiovascular Cell Therapy Research Network (CCTRN)]
通讯作者：
Cardiovascular Cell Therapy Research Network (CCTRN)
DOI：
10.3109/14653240903511952
发表时间：
2010-05
期刊：
Cytotherapy
影响因子：
4.5
作者：
[Stroncek D, Berlyne D, Fox B, Gee A, Heimfeld S, Lindblad R, Loper K, McKenna D Jr, Rooney C, Sabatino M, Wagner E, Whiteside T, Wood D, Heath-Mondoro T]
通讯作者：
Heath-Mondoro T
DOI：
10.1001/jama.2011.1670
发表时间：
2011-11-16
期刊：
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
影响因子：
120.7
作者：
[Traverse, Jay H., Henry, Timothy D., Ellis, Stephen G., Pepine, Carl J., Willerson, James T., Zhao, David X. M., Forder, John R., Byrne, Barry J., Hatzopoulos, Antonis K., Penn, Marc S., Perin, Emerson C., Baran, Kenneth W., Chambers, Jeffrey, Lambert, Charles, Raveendran, Ganesh, Simon, Daniel I., Vaughan, Douglas E., Simpson, Lara M., Gee, Adrian P., Taylor, Doris A., Cogle, Christopher R., Thomas, James D., Silva, Guilherme V., Jorgenson, Beth C., Olson, Rachel E., Bowman, Sherry, Francescon, Judy, Geither, Carrie, Handberg, Eileen, Smith, Deirdre X., Baraniuk, Sarah, Piller, Linda B., Loghin, Catalin, Aguilar, David, Richman, Sara, Zierold, Claudia, Bettencourt, Judy, Sayre, Shelly L., Vojvodic, Rachel W., Skarlatos, Sonia I., Gordon, David J., Ebert, Ray F., Kwak, Minjung, Moye, Lemuel A., Simari, Robert D.]
通讯作者：
Simari, Robert D.
PROTECTIVE TREATMENT FOR POLYMERIC SOLIDS
-
批准号：3508395
-
项目类别：
-
资助金额：$22.97万
-
财政年份：1985
-
负责人：JOHN B NEWKIRK
-
依托单位：
PROTECTIVE TREATMENT FOR POLYMERIC SOLIDS
-
批准号：3508396
-
项目类别：
-
资助金额：$21.06万
-
财政年份：1985
-
负责人：JOHN B NEWKIRK
-
依托单位：