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BONE INGROWTH STIMULATION USING ELECTROMAGNETIC FIELDS

BONE INGROWTH STIMULATION USING ELECTROMAGNETIC FIELDS
使用电磁场刺激骨向生长
批准号:
3490550
负责人:
ALLAN M WEINSTEIN
金额:
$4.91万
依托单位国家:
美国
项目类别:
财政年份:
1990
资助国家:
美国
项目状态:
已结题
起止时间:
1990-09-20 至 1991-05-03

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中文摘要
翻译
使用多孔涂层来提供连接机构 在过去的几年里,患病关节的置换数量急剧增加。 几年来,它一直在这样做,预计今后还会继续这样做。确实有 美国每年进行30万例髋关节和膝关节置换术 据估计,这些植入物中有50%依赖于骨向内生长 种植体与患者骨之间的附着机制。 在多孔涂层植入物中增强骨生长的能力将是 对病人有很大的好处。随着骨骼内长的增强,更早 允许返回负重状态,从而缩短住院时间和 总体上较短的恢复期。此外,更广泛和 可预测的骨长入可以确保固定和最终的长期 种植体的成功,这是骨向内生长的最初目标 定格。 这项研究的目的是论证共振的可行性。 电磁场刺激骨向内生长,从而增强 非固井水泥的性能 关节置换。植入物将被放置在12岁的双侧股骨 成年灰狗。动物将在3周和6周时被处死, 骨长入程度11可通过力学测试和 组织学分析。
英文摘要
The use of porous coatings to provide the attachment mechanism for the replacement of diseased joints has increased dramatically in the past few years and it is expected to continue to do so in the future. There are 300,000 hip and knee replacements performed annually in the united States and it is estimated that 50% of these implants rely on bone ingrowth as the mechanism of attachment between the implant and the patient bone. The ability to enhance bone ingrowth into porous coated implants would be of substantial benefit to the patient. With enhanced bone ingrowth, earlier return to weightbearing d be allowed leading to shorter hospital stays and an overall shorter convalescence. Additionally, more extensive and predictable bone ingrowth could insure fixation and ultimate long term success of the implant which was the original goal of bone ingrowth fixation. The aim of this study is to demonstrate the feasibility of resonant electromagnetic fields to stimulate bone ingrowth and thereby enhance the performance of noncemented joint replacement. Implants will be placed bilaterally in the femoral of 12 adult greyhounds. Animals will be sacrificed at 3 and 6 weeks and the degree of bone ingrowth 11 be evaluated using mechanical testing and histological analysis.
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