MINIATURIZED BENCH-TOP ANALYTICAL CELL SORTER

小型台式分析细胞分选机

• 批准号: 3492741
• 负责人: PERRY R SKEATH
• 金额: $ 4.47万
• 依托单位: SPRAYCHIP SYSTEMS CORPORATION
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-01-10 至 1992-01-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3492741
• 关键词: biomedical equipment development; biotechnology; cell sorting; clinical biomedical equipment; diagnosis design /evaluation; flow cytometry; fluid flow; fluorescence; heavy metals; microscopy; plastics; semiconduction; silicon; suspensions

The purpose of this work is to develop an instrument which integrates flow cytometry, cell sorting, and image cytometry. The system sorts cells in a liquid medium using fluorescence cytometry. The system then presents the selected cells for microscopic examination. The technological innovation consists of (1) a single assembly which identifies, sorts, and accumulates selected cells (2) the entire device is compact so that it may be mounted directly on a microscope stage. The ability to sort and accumulate cells of interest in the field of the microscope for image analysis can greatly expedite the evaluation of a specimen. This would be useful in many types of tumor analysis including lymphomas, Hodgkin's disease, myeloma, hair cell leukemia, and mycosis fungoids.

本工作的目的是开发一种集成流的仪器