课题基金 / 基金详情

ALEXANDRITE LASER FOR PDT CANCER RESEARCH

ALEXANDRITE LASER FOR PDT CANCER RESEARCH
用于 PDT 癌症研究的亚历山大石激光器
批准号:
3491853
负责人:
JOHN C WALLING
金额:
$5.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1988
资助国家:
美国
项目状态:
已结题
起止时间:
1988-05-15 至 1988-11-14

项目摘要

项目成果

JOHN C WALLING的其他基金

相关文献

中文摘要
翻译
我们的目标是制定一种更有效的方法来
英文摘要
Our objectives is to develop a more effective approach to photodynamic therapy (PDT) of cancer by combining two emergent technologies: a) New photosensitizers with improved photochemical characteristics which operate in the deep red wavelength region where body tissue is most translucent, and b) The alexandrite laser1, a superior wavelength tunable solid state laser source in this spectral region. Included among these new photosensitizers are verdins2, purpurins3, bacteriochlorin4, silicon naphthalocyanine5,6,7 and bacteriopheophorbide8, with peak absorption, respectively, at xxxx, 715nm, 765nm, and 755nm. While an emergent technology, laboratory alexandrite lasers, continuously tunable from 710nm to over 800nm in pulsed mode and 740nm to 800nm is continuous mode, have demonstrated performance will within application requirements, and are well adapted to fiber optic delivery. The objectives of this first phase are the construction of a suitably configured alexandrite laser for PDT experimentation, and the test and evaluation of this laser with the verdins and other appropriate photosensitizers using laboratory rats by established methods. The results will guide further development of the laser, beam delivery apparatus and treatment protocol, leading, potentially, to a cost effective clinical laser for PDT.
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IMPROVING UV AND VIOLET SOURCES OF CYTOMETRY
  • 批准号:
    6394663
  • 项目类别:
  • 资助金额:
    $11.18万
  • 财政年份:
    1997
  • 负责人:
    JOHN C WALLING
  • 依托单位:
IMPROVING UV AND VIOLET SOURCES OF CYTOMETRY
  • 批准号:
    6212330
  • 项目类别:
  • 资助金额:
    $37.38万
  • 财政年份:
    1997
  • 负责人:
    JOHN C WALLING
  • 依托单位:
ALEXANDRITE LASER LITHOTRIPTER
  • 批准号:
    2142520
  • 项目类别:
  • 资助金额:
    $5.0万
  • 财政年份:
    1990
  • 负责人:
    JOHN C WALLING
  • 依托单位: