EXPERT RADIOLOGY ASSISTANT: PHASE II

描述(改编自申请人的摘要)：建议进行以下研究 计算机辅助放射学专家系统的研制 乳腺癌的诊断使用临床表现、X光乳房X光检查、 和超声图像作为输入数据。基于鼓励可行性 结果表明，一期原型系统产生了 可与放射科专家相提并论的解释，建议将 该系统能够在更复杂的诊断情况下，纳入数据 为乳房X光摄影数据的统计分析提供基础，以优化 诊断规则，提炼取证方法，完善 用户界面，并调查客观形象的作用 分析。 第二阶段的具体目标旨在为以下方面提供实验证据 确定专家系统技术在乳腺癌诊断中的作用， 培训住院医师，管理和报告检查数据，以及 协助检测和量化异常。由此产生的 专家系统将进行广泛的测试，包括追溯和 前瞻性地，使用临床数据来评估实际可实现的 诊断的准确性、总体临床效用和潜在的 商业化。

DESCRIPTION (Adapted from applicant's abstract): Research is proposed for the development of a computer-based expert radiology assistant to aid in the diagnosis of breast cancer using clinical findings, x-ray mammograms, and ultrasound images as input data. Based upon encouraging feasibility results which demonstrated that the Phase I prototype system produced interpretations comparable to expert radiologists, it is proposed to extend the system to more complex diagnostic situations, to incorporate a data base for statistical analysis of mammographic data, to optimize the diagnostic rules, to refine the methods of combining evidence, to improve the user interface, and to investigate the role of objective image analysis. Specific aims of Phase II are designed to provide experimental evidence to determine the role of expert system technology in breast cancer diagnosis, training of residents, management and reporting of examination data, and assistance in detecting and quantifying of abnormalities. The resulting expert system will be extensively tested, both retrospectively and prospectively, using clinical data to evaluate the practically attainable diagnostic accuracy, overall clinical utility, and potential for commercialization.