DEVELOPMENT OF A COMPUTERIZED NASAL RESISTANCE SYSTEM

尽管成千上万的美国人遭受着 过敏、哮喘、息肉病、鼻畸形和其他气道疾病 限制疾病，目前没有低成本的商业上可获得的 用于定量评估鼻气流的集成计算机化系统 功能 基于男性和女性受试者的定量规范性数据 鼻功能正常和异常的患者无法进行任何测量 从目前可用的商业系统中获得的气流， 这种系统存在许多技术和理论问题。 该项目的总体目标是开发， 商业配送，成本低，实用，一体化电脑化 有效的标准数据可用的计量系统。 同相 在SBIRP项目中，我们将启动该系统的开发。 在第二阶段，我们将完成该系统的开发， 鼻功能正常和异常个体的人群标准。 在第三阶段，开发的系统将用于商业用途。 分布 本提案仅要求为第一阶段提供资金， 尽管在第II阶段进行的研究在 研究计划概述整个研究的策略 程序.

Despite the fact that hundreds of thousands of Americans suffer from allergies, asthma, polyposis, nasal deformities, and other airway restricting maladies, there is presently no low cost commercially available integrated computerized system for quantitatively assessing nasal airflow function. Quantitative normative data based upon male and female subjects with normal and abnormal nasal function are not available for any measures of airflow derived from currently available commercial systems, and all such systems suffer from a number of technical and theoretical problems. The overall purpose of this project is to develop, for subsequent commercial distribution, a low cost, practical, and integrated computerized rhinometric system for which valid normative data are available. In Phase I of this SBIRP project we will initiate the development of this system. In Phase II we will complete the development of this system and establish population norms for individuals with normal and abnormal nasal function. During Phase III the developed system will be made available for commercial distribution. Funding is requested in this proposal for only Phase I, although studies to be conducted in Phase II are briefly mentioned in the Research Plan to provide an overview of the strategy of the entire research program.