Phase III of The Directed Assembly EPRSC Grand Challenge Network: From Discovery to Translation

定向组装EPRSC大挑战网络第三阶段：从发现到翻译

• 批准号: EP/P007279/1
• 负责人: Charalampos Makatsoris
• 金额: $ 32.37万
• 依托单位: CRANFIELD UNIVERSITY
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FP007279%2F1
• 关键词: Phase; III; Directed; Assembly; EPRSC

The vision of the Network is to be able to control the assembly of matter with sufficient certainty and precision to allow preparation of materials and molecular assemblies with far more sophisticated and tuneable properties and functions than are accessible in materials synthesised using current methods.In this Grand Challenge we aim to gain unprecedented control of the assembly of molecules that are the building blocks of many functional materials, consumer and industrial products. We start by understanding the assembly of the very small, but methods we explore will allow production of new types of useful materials at a whole range of length scales from the nanoscale to the everyday. Such materials will have outstanding impact in areas of societal importance such as personalised healthcare and food production, transport systems and fuel production, housing construction and consumer electronics.Through this intelligent approach to design we will compete effectively with the USA, Japan and mainland Europe to place the UK firmly at the forefront of developments in the areas of manufacturing, healthcare and energy.The added value that the Network provides is in gathering the widest group of internationally-leading expert scientists from across a range of disciplines in the UK, and providing them with a challenge, a focus and a vision that they help shape.On-going economic prosperity in the UK is critically dependent on having a competitive, high-tech manufacturing industry.Some areas of the Directed Assembly Network's activities address barriers to progress in existing industries; others will create the transformative industries of the future. Society is challenged by a growing and aging population, and through declining natural resources. The goals we reach for will drive great breakthroughs in healthcare and offer alternatives to harvesting our limited reserves.The UK has already been identified as being world-class or world-leading in many of the individual disciplines needed to tackle these targets, but real breakthroughs will only be made by harnessing interdisciplinary excellence from across the UK - the Directed Assembly Network is key to the formation and maintenance of this interdisciplinary community. Other countries are already investing heavily in programmes to progress materials science; by adopting the recommendations above, the UK can enhance its scientific capability and keep pace at international levels, develop absorptive capacity and retain the competitive advantage needed to be a world player in the field of future manufacturing.Since its launch in 2010, the DAGCN has become embedded into the culture of those working in Directed Assembly and is known as a place to go to for mentoring, advice and support. The Network has awarded 23 pump-priming grants over the last four years. These, together with meetings have been instrumental in leveraging approximately £50M of major grant funding. A community of 970 multi-disciplinary members from across the UK, including 112 industry members and 260 early career researchers has been engaged, nurtured and brought together with a common aim: the Directed Assembly Grand Challenge. Over 45 meetings have been held directly that have led to 80 new collaborations. A culture change has been widely noted since the inception of the Network in both the way rival companies now commonly work together at pre-competitive stages, and, different types of scientists now see each-other as invaluable towards achieving strong relationships and results. Researcher mobility through travel grants and pump-priming projects has contributed to data and equipment sharing, notwithstanding the skills development of the UK research base. The vast 970 community has been engaged consistently and led to a Roadmap setting out the vision for the next 5-50 years.

该网络的愿景是能够以足够的确定性和精确度控制物质的组装，从而制备出比使用当前方法合成的材料更复杂和可调节的特性和功能的材料和分子组装体。在这项重大挑战中，我们的目标是获得对分子组装的前所未有的控制，这些分子是许多功能材料、消费品和工业产品的构建模块。我们首先了解非常小的组装，但我们探索的方法将允许生产从纳米尺度到日常尺度的各种长度尺度的新型有用材料。此类材料将在个性化医疗保健和食品生产、运输系统和燃料生产、住房建设和消费电子产品等具有社会重要性的领域产生突出影响。通过这种智能设计方法，我们将与美国、日本和欧洲大陆进行有效竞争，使英国牢牢地处于制造、医疗保健和能源领域发展的前沿。该网络提供的附加价值在于聚集了来自世界各地的最广泛的国际领先专家科学家群体 英国的一系列学科，并为他们提供了挑战、焦点和他们帮助塑造的愿景。英国持续的经济繁荣在很大程度上取决于拥有具有竞争力的高科技制造业。定向装配网络活动的某些领域解决了现有行业进步的障碍；其他人将创造未来的变革性产业。社会面临人口增长和老龄化以及自然资源减少的挑战。我们实现的目标将推动医疗保健领域的重大突破，并为收获我们有限的储备提供替代方案。英国已被认为在实现这些目标所需的许多单个学科方面处于世界一流或世界领先地位，但只有通过利用英国各地的跨学科卓越才能取得真正的突破 - 定向组装网络是形成和维护这个跨学科社区的关键。其他国家已经在材料科学进步项目上投入巨资。通过采用上述建议，英国可以增强其科学能力并与国际水平保持同步，发展吸收能力并保留成为未来制造领域世界参与者所需的竞争优势。自 2010 年推出以来，DAGCN 已融入直接装配工作人员的文化中，并被认为是寻求指导、建议和支持的地方。该网络在过去四年中授予了 23 项泵启动赠款。这些活动与会议一起，在利用大约 5000 万英镑的主要赠款资金方面发挥了重要作用。来自英国各地的 970 名多学科成员（包括 112 名行业成员和 260 名早期职业研究人员）组成的社区已经参与、培养和聚集在一起，以实现一个共同目标：定向组装大挑战。直接举行了超过 45 场会议，促成了 80 项新的合作。自该网络成立以来，文化变革已引起广泛关注，竞争对手公司现在通常在竞争前阶段合作，而且不同类型的科学家现在认为彼此对于实现牢固的关系和成果至关重要。尽管英国研究基地的技能不断发展，但通过旅行补助和启动项目进行的研究人员流动仍有助于数据和设备共享。广大的 970 社区一直积极参与，并制定了路线图，制定了未来 5-50 年的愿景。

项目成果

Effects of the homopolymer molecular weight on a diblock copolymer in a 3D spherical confinement

• DOI: 10.1186/s13065-019-0541-7
• 发表时间: 2019-02
• 期刊: BMC Chemistry
• 影响因子: 4.6
• 作者: D. Ly;C. Makatsoris

Directed Assembly Network phase three launch: a round-up of success to date and strategy for the future.

• DOI: 10.1186/s13065-017-0310-4
• 发表时间: 2017-08-04
• 期刊: Chemistry Central journal
• 作者: Rose JAR;Raithby PR;Makatsoris C
• 通讯作者: Makatsoris C