REDUCED SPECKLE EFFECT ON ULTRASOUND LESION DETECTION

散斑是所有相干成像系统的基本特性。它 降低对比度分辨率，从而降低低对比度的可检测性 损伤。斑点也被认为是一种重大的分心和 阻碍了超声成像的新应用。四分体有 证明了一种非线性的迭代算法可以有效地 在不显著丢失细节的情况下减少超声图像中的斑点。 这样的发展可能会提高脑血管疾病的诊断价值。 为专业观众提供超声波，并将简化图像解释 非专业人士。拟议的工作有三个目标：1)适应这一点 针对超声成像的特殊要求的算法 (例如，空间分辨率不一致、高动态范围等)；2) 设计了一种适合实时相干斑抑制的硬件体系结构； 3)临床验证本方法的有效性。 提高发现低对比度、局灶性病变的可能性。二 将调查主要应用领域：1) 术中/腹腔镜扫描肝脏和2)乳房 放映。成像将使用高频(7.5-12 MHz)， 高分辨率系统。拟议的项目是一项合作努力。 硬件设计人员、算法开发人员和最终用户之间 放射学和外科。

Speckle is a fundamental property of all coherent imaging systems. It reduces contrast resolution and thereby the detectability of low contrast lesions. Speckle is also perceived as a significant distraction and impediment for new applications of ultrasound imaging. TETRAD has demonstrated that a non-linear, iterative algorithm can effectively reduce speckle in ultrasound images without significant loss of detail. Such a development could potentially improve the diagnostic value of ultrasound for expert viewers and would ease image interpretation for the non-expert. The proposed work has three goals: 1) to adapt this algorithm to the special requirements imposed by ultrasound imaging (e.g., non-uniform spatial resolution, high dynamic range, etc.); 2) to design a hardware architecture suitable for real-time speckle reduction; and 3) to clinically demonstrate the effectiveness of this method for improving the probability of detecting low contrast, focal lesions. Two major application areas will be investigated: 1) intraoperative/laparoscopic scanning of the liver and 2) breast screening. Imaging will be performed using high frequency (7.5-12 MHz), high resolution systems. The proposed project is a collaborative effort between hardware designers, algorithm developers, and end-users in radiology and surgery.