Ultrasound and Nerve Stimulator Guide
Ultrasound and Nerve Stimulator Guide
批准号:
6525445
负责人:
LAWRENCE J BUSSE
金额:
$21.83万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-04-01 至 2005-02-28
关键词:
bioengineering /biomedical engineering bioimaging /biomedical imaging biomedical equipment development biomedical equipment safety biophysics cardiovascular imaging /visualization cardiovascular system clinical trials conduction anesthesia disease /disorder prevention /control drug delivery systems electrical measurement electronic stimulator human subject human therapy evaluation intravenous anesthesia neuromuscular stimulator outcomes research patient oriented research peripheral nervous system postoperative complications surgery material /equipment time resolved data
中文摘要
描述(由申请人提供):区域麻醉(RA)是一种强大的
减少围手术期和慢性疼痛的技术。RA提供
对患者有显著好处,因为它只需要轻微的镇静和
从而降低了术后并发症的发生率。尽管
这些优势,只有5%-20%的符合条件的患者会患上RA。选择
因为RA主要取决于实践者对应用该方法的信心。
这项拟议的研究将开发一种设备,将改善医生
通过在RA期间提供实时反馈来增强信心。该区块的成功:
取决于定位深部放置的神经以阻断周围神经或
神经血管束用于神经丛的阻断,同时避开周围的生命
结构。由于靶神经与主要血管紧密相连,
将结合使用多普勒超声(用于
远距离方向)和电刺激以确认
针头摆放。一种多普勒定向神经刺激器(DDNS)
将建立连续波多普勒法并进行临床研究
研究其对RA的指导作用。一种基于脉冲多普勒技术的DDNS样机
将进行建造和测试,以提高性能和安全性。成功
第二阶段的完成将导致为RA推出一种新产品
送货。
建议的商业应用:
RA对患者和付款人都有潜在的好处,因为它的使用促进了
康复、缩短住院时间和出色的疼痛控制。总成本
约为全麻相关费用的1/3。最新进展
用于引导RA的一次性装置将产生商业上可行的产品,
这将增加RA的使用并降低与手术相关的成本
麻醉和术后护理。
英文摘要
DESCRIPTION (Provided by the Applicant): Regional anesthesia (RA) is a powerful
technique to reduce both perioperative and chronic pain. RA provides
significant benefits to patients since it requires only light sedation and
thereby results in a low incidence of postoperative complications. Despite
these advantages, only 5-20 percent of eligible patients receives RA. Selection
for RA depends primarily on a practitioner's confidence in applying the method.
The proposed research will develop a device that will improve physician
confidence by providing realtime feedback during RA. The success of the block:
depends on locating the deeply placed nerves for peripheral nerve blockade or
the neurovaseular bundle for plexus blockade, while avoiding surrounding vital
structures. Since target nerves lie in close proximity to major blood vessels,
guidance will be provided using a combination of Doppler ultrasound (for
long-range direction) and electrical nerve stimulation for confirmation of
needle placement. A Doppler Directed Nerve Stimulator (DDNS) using the
continuous-wave Doppler method will be built and a clinical study undertaken to
study its efficacy for guiding RA. A DDNS prototype using pulsed-wave Doppler
will be built and tested for improved performance and safe about. Successful
completion of Phase II will lead to the introduction of a new product for RA
delivery.
PROPOSED COMMERCIAL APPLICATION:
RA potentially benefits both patients and payers since its use promotes rapid
recovery, shortened hospital stays and excellent pain control. The overall cost
of RA is about 1/3 of costs associated with general anesthesia. The development
of a disposable device for guiding RA will result in a commercially viable product,
which will increase the use of RA and decrease the costs associated with surgical
anesthesia and post-operative care.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Development of a rapid, scalable, and deployable point-of-care blood volume diagnostic for monitoring postpartum and trauma-related hemorrhage
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批准号:10603819
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项目类别:
-
资助金额:$23.13万
-
财政年份:2023
-
负责人:LAWRENCE J BUSSE
-
依托单位:
Ultrasound and Nerve Stimulator Guide
-
批准号:6337470
-
项目类别:
-
资助金额:$21.31万
-
财政年份:1999
-
负责人:LAWRENCE J BUSSE
-
依托单位:
ULTRASOUND AND NERVE STIMULATOR GUIDE
-
批准号:2785411
-
项目类别:
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资助金额:$9.96万
-
财政年份:1999
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负责人:LAWRENCE J BUSSE
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依托单位:
REDUCED SPECKLE EFFECT ON ULTRASOUND LESION DETECTION
-
批准号:3506777
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项目类别:
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资助金额:$25.83万
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财政年份:1990
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负责人:LAWRENCE J BUSSE
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依托单位:
THREE-DIMENSIONAL INTRAVASCULAR IMAGING WITH ULTRASOUND
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批准号:3508743
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项目类别:
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资助金额:$2.67万
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财政年份:1990
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负责人:LAWRENCE J BUSSE
-
依托单位:
THREE-DIMENSIONAL INTRAVASCULAR IMAGING WITH ULTRASOUND
-
批准号:3508744
-
项目类别:
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资助金额:$23.38万
-
财政年份:1990
-
负责人:LAWRENCE J BUSSE
-
依托单位:
THREE-DIMENSIONAL INTRAVASCULAR IMAGING WITH ULTRASOUND
-
批准号:3501711
-
项目类别:
-
资助金额:$5.0万
-
财政年份:1990
-
负责人:LAWRENCE J BUSSE
-
依托单位:
THREE-DIMENSIONAL INTRAVASCULAR IMAGING WITH ULTRASOUND
-
批准号:3508742
-
项目类别:
-
资助金额:$21.86万
-
财政年份:1990
-
负责人:LAWRENCE J BUSSE
-
依托单位:
REDUCED SPECKLE EFFECT ON ULTRASOUND LESION DETECTION
-
批准号:2094329
-
项目类别:
-
资助金额:$24.17万
-
财政年份:1990
-
负责人:LAWRENCE J BUSSE
-
依托单位: